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Disease
Dyspnea
Late-stage therapeutic developmentEmerging research
4
Publications
16
Clinical trials
2
Related conditions
10
Associated genes
2021
Latest publication
Latest activity
betaRecent clinical, regulatory, research and industry developments relating to this disease.
Clinical trial2026-09-25Status changed to Active, not recruiting · ClinicalTrials.gov
What's happening now
An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.
Executive briefingUpdating summary…Momentum: Low
Key developments
- 3 clinical trials expected to report results, the earliest in Q1 2028.
- 2 industry developments reported.
Upcoming Milestones
- Q1 2028Early Exercise-based Rehabilitation in High-risk Patients Hospitalized for Acute Pulmonary Embolism: a Pragmatic Multicenter Randomized Partially Blinded Superiority Trial
- Q2 2028129Xe Gas Exchange MRI to Visualize Cardiopulmonary Function
- Q1 2029Effect of PDE5 Inhibitor on Respiratory Symptoms in COPD Complicated by Pulmonary Hypertension
Major developments
Major trial resultsImportant
Results posted2026-06-11
Upcoming trial readoutImportant
Results expected Q1 20292026-05-15
Clinical MilestonesViewHide
Results posted
- 2026-06-11A Randomized Controlled Trial of Dexamethasone for Dyspnea in Cancer PatientsResults posted
Results expected
- 2026-06-12Early Exercise-based Rehabilitation in High-risk Patients Hospitalized for Acute Pulmonary Embolism: a Pragmatic Multicenter Randomized Partially Blinded Superiority TrialResults expected Q1 2028
- 2026-05-15Effect of PDE5 Inhibitor on Respiratory Symptoms in COPD Complicated by Pulmonary HypertensionResults expected Q1 2029
- 2026-02-04129Xe Gas Exchange MRI to Visualize Cardiopulmonary FunctionResults expected Q2 2028
Industry & MarketViewHide
- 2026-10-13Morphine Underused in ED for End-of-Life DyspneaIndustry · Medscape Medical News
- 2026-09-09Laughter therapy improves dyspnea, health status in COPDIndustry · Healio Pulmonology
Activity timeline6
- 2026-10-13IndustryMorphine Underused in ED for End-of-Life DyspneaIndustry · Medscape Medical News
- 2026-09-09IndustryLaughter therapy improves dyspnea, health status in COPDIndustry · Healio Pulmonology
- 2026-06-12ClinicalEarly Exercise-based Rehabilitation in High-risk Patients Hospitalized for Acute Pulmonary Embolism: a Pragmatic Multicenter Randomized Partially Blinded Superiority TrialResults expected Q1 2028
- 2026-06-11ClinicalA Randomized Controlled Trial of Dexamethasone for Dyspnea in Cancer PatientsResults posted
- 2026-05-15ClinicalEffect of PDE5 Inhibitor on Respiratory Symptoms in COPD Complicated by Pulmonary HypertensionResults expected Q1 2029
- 2026-02-04Clinical129Xe Gas Exchange MRI to Visualize Cardiopulmonary FunctionResults expected Q2 2028
Clinical trials
The current development programme across all trial phases.
Clinical programme
16
4
8
6
Late-stage studies
Recruiting
Recently completed
Research activity
Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.
Publications over time
Most influential
Recent publications
Major themes3
- Disease Outbreaks1
- Hospitalization1
- Survivors1
Leading journals4
- JAMA1
- PLoS medicine1
- Scientific reports1
- The New England journal of medicine1
Leading researchers8
- Adachi D1
- Ayers M1
- Baudry E1
- Becquemont L1
- Bellin MF1
- Beurnier A1
- Brunham RC1
- Chan AK1
Affiliations (unnormalised)6
- Center for Infectious Medicine1
- Center for Neuroregeneration1
- Emory University School of Medicine1
- Harvard T.H. Chan School of Public Health1
- Instituto Nacional de Cancerología1
- National Autonomous University of Mexico1
Associated genes
Genes associated with this disease in the canonical knowledge graph (Open Targets evidence). Number shows the association score.
Related conditions
Diseases frequently studied alongside this one. Number shows shared papers.
Reference
Authoritative identity, definition & identifiers.
Defined in MeSH
Difficult or labored breathing.
Identifiers
References & data sources
- Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
- Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
- Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
- Related entities are derived from literature co-mention (studied together) — associative, not causal.