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Disease

Enteritis

Late-stage therapeutic developmentEmerging research
MeSHEnteritis
2
Publications
14
Clinical trials
12
Associated genes
2
Related proteins
2023
Latest publication
Current focus
Therapeutic developmentInflammation & immunityMetabolic & lifestyle factors
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this disease.

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

Executive briefingUpdating summary…Momentum: Low
Key developments
  • 2 clinical trials expected to report results, the earliest in Q4 2028.
Upcoming Milestones
Clinical Milestones2View
Results expected 2
Activity timeline2

Clinical trials

10 sponsors · 1 new · 0 completed in the last 12 months (net +1)

The current development programme across all trial phases.

Clinical programme
14
All trials
2
Active
3
Late-stage
6
Completed
Recently completed

A Phase 1, Double-Blind, Randomized, Placebo-Controlled, Multiple Ascending Dose Study to Assess the Pharmacokinetics, Safety, and Tolerability of Orally Administered SYN 020 Delayed Release Capsules in Healthy Subjects

Phase 1 · Completed · Theriva Biologics, Inc.

A Clinical Trial to Assess Three Different Doses of OPS-2071 in Patients With Bacterial Enteritis

Phase 2 · Completed · Otsuka Pharmaceutical Co., Ltd.

A Phase 2b Controlled Efficacy Study of Intradermally Delivered ETEC Fimbrial Tip Adhesin Vaccine Against Experimental Challenge With ETEC H10407 in Healthy Adult Volunteers

Phase 2 · Completed · U.S. Army Medical Research and Development Command

A Randomized Double-blind Trial Comparing the Effect of Oral Dimenhydrinate Versus Placebo in Children With Moderate Vomiting Due to Acute Gastroenteritis

Phase 4 · Completed · St. Justine's Hospital

A Phase 1/2 Study to Evaluate Escalating Doses of SGX201 [Delayed Release Oral Beclomethasone Dipropionate (BDP)] for Prevention of Signs and Symptoms of Acute Enteritis in Patients With Rectal Cancer Treated With Combined Chemotherapy and Radiation Therapy

Phase 1/2 · Completed · Soligenix

The Treatment Effect of Bio-Three on Children With Enteritis Due to Salmonella or Rotavirus or Any Unknown Reason

Phase 4 · Completed · Kaohsiung Veterans General Hospital.

Research activity

2 papers

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Publications over time
20152023
Major themes4
  • Gastroenteritis1
  • Immune Checkpoint Inhibitors1
  • Insulin Resistance1
  • Neoplasms1
Leading journals2
  • Gut1
  • The New England journal of medicine1
Leading researchers8
  • Amant F1
  • Anhê FF1
  • Baarslag MA1
  • Beijnen JH1
  • Borgers JSW1
  • Buitelaar PLM1
  • de Groot JWB1
  • Desjardins Y1
Affiliations (unnormalised)4
  • Amalia Children's Hospital1
  • Cardiology Axis of the Quebec Heart and Lung Institute1
  • Institute of Nutrition and Functional Foods1
  • Research Centre1

Associated genes

12 matches

Genes associated with this disease in the canonical knowledge graph (Open Targets evidence). Number shows the association score.

IL23R0.51NOD20.49ACOXL0.35GEMIN50.34GPR350.32IRGM0.32ARK2C0.30RBM190.30C12orf750.30HERPUD20.30STK390.29MCTP20.29

Disease biology

2 matches

Proteins whose encoding gene is associated with this disease, reached through the canonical gene→disease graph. Number shows the gene's association score.

Nucleotide-binding oligomerization domain-containing protein 2via NOD20.49Organic anion transporter 3via SLC22A80.14

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

Inflammation of any segment of the SMALL INTESTINE.

Identifiers
MeSHEnteritis
References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.