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Disease
Enteritis
Late-stage therapeutic developmentEmerging research
2
Publications
14
Clinical trials
2023
Latest publication
Current focus
Therapeutic developmentInflammation & immunityMetabolic & lifestyle factors
Latest activity
betaRecent clinical, regulatory, research and industry developments relating to this disease.
Severe Immune-Related Enteritis after In Utero Exposure to Pembrolizumab.
Research2023-11-01The New England journal of medicine
What's happening now
An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.
Executive briefingUpdating summary…Momentum: Low
Key developments
- 2 clinical trials expected to report results, the earliest in Q4 2028.
Major developments
Upcoming trial readoutImportant
Results expected Q4 20282026-03-27
Upcoming trial readoutImportant
Results expected Q1 20312025-12-11
Clinical MilestonesViewHide
Results expected
- 2026-03-27Efficacy and Safety of Thalidomide Combined With Glutamine in the Treatment of Radiation Intestinal Injury: a Single-center, Open-label, Randomized Controlled StudyResults expected Q4 2028
- 2025-12-11A Phase 2 Randomized Stepped Wedge Study of Emapalumab in APECED EnteritisResults expected Q1 2031
Activity timeline2
- 2026-03-27ClinicalEfficacy and Safety of Thalidomide Combined With Glutamine in the Treatment of Radiation Intestinal Injury: a Single-center, Open-label, Randomized Controlled StudyResults expected Q4 2028
- 2025-12-11ClinicalA Phase 2 Randomized Stepped Wedge Study of Emapalumab in APECED EnteritisResults expected Q1 2031
Clinical trials
The current development programme across all trial phases.
Clinical programme
14
2
3
6
Late-stage studies
Recruiting
Recently completed
Research activity
Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.
Publications over time
20152023
Most influential
Major themes4
- Gastroenteritis1
- Immune Checkpoint Inhibitors1
- Insulin Resistance1
- Neoplasms1
Leading journals2
- Gut1
- The New England journal of medicine1
Leading researchers8
- Amant F1
- Anhê FF1
- Baarslag MA1
- Beijnen JH1
- Borgers JSW1
- Buitelaar PLM1
- de Groot JWB1
- Desjardins Y1
Affiliations (unnormalised)4
- Amalia Children's Hospital1
- Cardiology Axis of the Quebec Heart and Lung Institute1
- Institute of Nutrition and Functional Foods1
- Research Centre1
Reference
Authoritative identity, definition & identifiers.
Defined in MeSH
Inflammation of any segment of the SMALL INTESTINE.
Identifiers
References & data sources
- Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
- Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
- Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
- Related entities are derived from literature co-mention (studied together) — associative, not causal.