IRGM

Gene

immunity related GTPase M

HGNCHGNC:29597 EnsemblENSG00000237693 NCBI Gene345611

Locus: gene with protein productLocation: 5q33.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asIRGM1 · LRG47 · LRG-47 · IFI1

View full nomenclature history (5)

Previous symbolsIRGM1

Alias symbolsLRG47, LRG-47, IFI1

Previous namesimmunity-related GTPase family, M1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Inflammatory Bowel Diseases

Spondylitis, Ankylosing

Cholangitis, Sclerosing

Infections

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.