Disease

Epilepsies, Myoclonic

Late-stage therapeutic developmentEmerging research

MeSHEpilepsies, Myoclonic

Publications

Clinical trials

2023

Latest publication

Latest activity

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Recent clinical, regulatory, research and industry developments relating to this disease.

An in silico and in vitro human neuronal network model reveals cellular mechanisms beyond NaV1.1 underlying Dravet syndrome.

Research2023-07-06Stem cell reports

International League Against Epilepsy classification and definition of epilepsy syndromes with onset in childhood: Position paper by the ILAE Task Force on Nosology and Definitions.

Research2022-05-03Epilepsia

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

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Clinical trials

1 sponsors · 0 new · 0 completed in the last 12 months (net +0)

The current development programme across all trial phases.

Clinical programme

All trials

Active

Late-stage

Completed

Late-stage studies

A Multicenter, Double-Blind, Randomized, Placebo-Controlled, Parallel-Group Study With Open-Label Extension Phase of Lorcaserin as Adjunctive Treatment in Subjects With Dravet Syndrome

Phase 3 · Terminated · Eisai Inc.

Research activity

2 papers

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Publications over time

20222023

Most influential

International League Against Epilepsy classification and definition of epilepsy syndromes with onset in childhood: Position paper by the ILAE Task Force on Nosology and Definitions.

Epilepsia · 2022 · 611 cites

An in silico and in vitro human neuronal network model reveals cellular mechanisms beyond NaV1.1 underlying Dravet syndrome.

Stem cell reports · 2023 · 15 cites

Recent publications

An in silico and in vitro human neuronal network model reveals cellular mechanisms beyond NaV1.1 underlying Dravet syndrome.

Stem cell reports · 2023 · 15 cites

International League Against Epilepsy classification and definition of epilepsy syndromes with onset in childhood: Position paper by the ILAE Task Force on Nosology and Definitions.

Epilepsia · 2022 · 611 cites

Major themes4

Epilepsies, Myoclonic2
Epilepsies, Partial1
Epilepsy, Absence1
Induced Pluripotent Stem Cells1

Leading journals2

Epilepsia1
Stem cell reports1

Leading researchers8

Auvin S1
Ciptasari U1
Cross HJ1
Doorn N1
Frega M1
Guerreiro M1
Gwer S1
Hirsch E1

Affiliations (unnormalised)6

Academic Center for Epileptology Kempenhaeghe1
Aga Khan University1
Albert Einstein College of Medicine and Montefiore Medical Center1
Austin Health and Royal Children's Hospital1
Bambino Gesù Children's Hospital1
Department of Clinical Neurophysiology1

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

A clinically diverse group of epilepsy syndromes characterized either by myoclonic seizures or by myoclonus in association with other seizure types. Myoclonic epilepsy syndromes are divided into three subtypes based on etiology: familial, cryptogenic, and symptomatic.

Identifiers

MeSHEpilepsies, Myoclonic

References & data sources

Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
Related entities are derived from literature co-mention (studied together) — associative, not causal.