Familial amyloid neuropathy
Also known as ATTRv amyloidosis, Corino de Andrade's disease, TTR amyloidosis, amyloid neuropathies, familial+12 more
ATTRv amyloidosis, Corino de Andrade's disease, TTR amyloidosis, amyloid neuropathies, familial, amyloidosis, hereditary, transthyretin-related, familial TTR-related amyloidosis, familial amyloid polyneuropathy, familial transthyretin amyloidosis, familial transthyretin-related amyloidosis, hATTR, hereditary TTR amyloid polyneuropathy, hereditary TTR amyloidosis, hereditary transthyretin amyloid polyneuropathy, paramyloidosis, transthyretin-related hereditary amyloidosis, hereditary amyloidosis, transthyretin-related.
What's happening now
An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.
Therapeutic landscape
Therapies with a regulatory footing for this condition, alongside the wider set of agents co-studied with it in the literature.
Approval — Attrogy is indicated for the treatment of hereditary transthyretin-mediated amyloidosis (… (2025)
Approval — Treatment of hereditary transthyretin-mediated amyloidosis (ATTRv) in adult patients with… (2025)
Approval — Treatment of hereditary transthyretin-mediated amyloidosis (hATTR amyloidosis) in adult p… (2022)
Accelerated approval — Treatment of stage 1 or Stage 2 polyneuropathy in adult patients with hereditary transthy… (2018)
Accelerated approval — Onpattro is indicated for the treatment of hereditary transthyretin-mediated amyloidosis… (2018)
Approval — Vyndaqel is indicated for the treatment of transthyretin amyloidosis in adult patients wi… (2011)
Regulatory timeline
Drug regulatory events matched to this condition by indication — EMA.
European Medicines Agency (CC BY 4.0). Events are matched to this condition by drug indication text — approvals/updates for drugs indicated for it, not disease-specific acts.
Associated genes
Genes associated with this disease in the canonical knowledge graph (Open Targets evidence). Number shows the association score.
Disease biology
Proteins whose encoding gene is associated with this disease, reached through the canonical gene→disease graph. Number shows the gene's association score.
Reference
Authoritative identity, definition & identifiers.
ATTRv amyloidosis, Corino de Andrade's disease, TTR amyloidosis, amyloid neuropathies, familial, amyloidosis, hereditary, transthyretin-related, familial TTR-related amyloidosis, familial amyloid polyneuropathy, familial transthyretin amyloidosis, familial transthyretin-related amyloidosis, hATTR, hereditary TTR amyloid polyneuropathy, hereditary TTR amyloidosis, hereditary transthyretin amyloid polyneuropathy, paramyloidosis, transthyretin-related hereditary amyloidosis, hereditary amyloidosis, transthyretin-related
- Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
- Related entities are derived from literature co-mention (studied together) — associative, not causal.