Gastrinoma
Recent clinical, regulatory, research and industry developments relating to this disease.
What's happening now
An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.
- 2 clinical trials with recent milestones (1 completed or reporting results).
Clinical MilestonesViewHide
- 2031-12-31ClinicalA Prospective Randomized Study of the Efficacy and Safety of 177Lu-DOTATOC With Either Standard or Personalized Dosing for the Treatment of Patients With Somatostatin Receptor Positive NETsWithdrawn
- 2026-02-25ClinicalA Randomized Phase II Study of Temozolomide or Temozolomide and Capecitabine in Patients With Advanced Pancreatic Neuroendocrine TumorsResults posted
Clinical trials
The current development programme across all trial phases.
Research activity
Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.
Major themes5
- Gastrinoma1
- Glucagonoma1
- Insulinoma1
- Neuroendocrine Tumors1
- Pancreatic Neoplasms1
Leading journals1
- Journal of neuroendocrinology1
Leading researchers8
- Bartsch DK1
- Castaño JP1
- Christ E1
- Faggiano A1
- Falconi M1
- Hofland J1
- Lamarca A1
- Perren A1
Affiliations (unnormalised)6
- Centre Hospitalier Annecy Genevois (CHANGE)1
- Department of Clinical and Molecular Medicine1
- Department of Oncology - OncoHealth Institute1
- ENETS Centre of Excellence1
- ENETS Centre of Excellence for Neuroendocrine and Endocrine Tumours1
- Hospital Universitario Reina Sofía1
Reference
Authoritative identity, definition & identifiers.
A GASTRIN-secreting neuroendocrine tumor of the non-beta ISLET CELLS, the GASTRIN-SECRETING CELLS. This type of tumor is primarily located in the PANCREAS or the DUODENUM. Majority of gastrinomas are malignant. They metastasize to the LIVER; LYMPH NODES; and BONE but rarely elsewhere. The presence of gastrinoma is one of three requirements to be met for identification of ZOLLINGER-ELLISON SYNDROME, which sometimes occurs in families with MULTIPLE ENDOCRINE NEOPLASIA TYPE 1; (MEN 1).
- Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
- Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
- Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
- Related entities are derived from literature co-mention (studied together) — associative, not causal.