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Disease
Gastroparesis
Late-stage therapeutic developmentEmerging research
3
Publications
17
Clinical trials
1
Related conditions
12
Associated genes
2024
Latest publication
Latest activity
betaRecent clinical, regulatory, research and industry developments relating to this disease.
Clinical Consequences of Delayed Gastric Emptying With GLP-1 Receptor Agonists and Tirzepatide.
Research2024-12-01The Journal of clinical endocrinology and metabolism
Research2024-04-29Gastrointestinal endoscopy
Research2023-11-27The Medical journal of Australia
What's happening now
An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.
Executive briefingUpdating summary…Momentum: Low
Key developments
- 3 clinical trials expected to report results, the earliest in Q4 2027.
- 2 industry developments reported.
Major developments
Upcoming trial readoutImportant
Results expected Q4 20272026-04-13
Major clinical milestoneImportant
Primary completion2026-10-01
Clinical MilestonesViewHide
Results expected
- 2026-04-16Low-dose Growth Hormone for the Treatment of GastroparesisResults expected Q4 2027
- 2026-04-13Treatment Protocol for the Compassionate Use of DomperidoneResults expected Q4 2027
- 2026-03-24Compassionate Use of Domperidone for Refractory GastroparesisResults expected Q4 2035
Recently completed
- 2026-10-01Examination of Programming with the Enterra® Therapy System in a Double-Blinded, Randomized, Prospective Study in the Treatment of Nausea and Vomiting Symptoms Using Gastric Electrical StimulationPrimary completion
- 2025-12-31A Multicenter, Open Label, 3-Month Safety Study with Tradipitant in Patients with Idiopathic or Diabetic GastroparesisPrimary completion
Industry & MarketViewHide
- 2026-10-30Naronapride Eases Gastroparesis Symptoms in Phase 2 TrialTrial news · Medscape Medical News
- 2026-10-21TAGSS Gets Breakthrough Device Designation for GastroparesisIndustry · Medscape Medical News
Activity timeline7
- 2026-10-30IndustryNaronapride Eases Gastroparesis Symptoms in Phase 2 TrialTrial news · Medscape Medical News
- 2026-10-21IndustryTAGSS Gets Breakthrough Device Designation for GastroparesisIndustry · Medscape Medical News
- 2026-10-01ClinicalExamination of Programming with the Enterra® Therapy System in a Double-Blinded, Randomized, Prospective Study in the Treatment of Nausea and Vomiting Symptoms Using Gastric Electrical StimulationPrimary completion
- 2026-04-16ClinicalLow-dose Growth Hormone for the Treatment of GastroparesisResults expected Q4 2027
- 2026-04-13ClinicalTreatment Protocol for the Compassionate Use of DomperidoneResults expected Q4 2027
- 2026-03-24ClinicalCompassionate Use of Domperidone for Refractory GastroparesisResults expected Q4 2035
- 2025-12-31ClinicalA Multicenter, Open Label, 3-Month Safety Study with Tradipitant in Patients with Idiopathic or Diabetic GastroparesisPrimary completion
Clinical trials
The current development programme across all trial phases.
Clinical programme
17
5
12
6
Late-stage studies
Recruiting
Recently completed
Research activity
Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.
Most influential
Recent publications
Major themes5
- Diabetes Mellitus, Type 22
- Gastric Emptying2
- Glucagon-Like Peptide-1 Receptor Agonists2
- Gastroparesis1
- Hypoglycemic Agents1
Leading journals3
- Gastrointestinal endoscopy1
- The Journal of clinical endocrinology and metabolism1
- The Medical journal of Australia1
Leading researchers8
- Addissie BD1
- Brown C1
- Confer BD1
- Diehl DL1
- Dove JT1
- Greenfield JR1
- Horowitz M1
- Jalleh RJ1
Affiliations (unnormalised)6
- Adelaide Medical School1
- Center for Obesity and Metabolic Research1
- Flinders Medical Centre1
- Garvan Institute of Medical Research1
- Geisinger Commonwealth School of Medicine1
- Geisinger Medical Center1
Associated genes
Genes associated with this disease in the canonical knowledge graph (Open Targets evidence). Number shows the association score.
Related conditions
Diseases frequently studied alongside this one. Number shows shared papers.
Reference
Authoritative identity, definition & identifiers.
Defined in MeSH
Chronic delayed gastric emptying. Gastroparesis may be caused by motor dysfunction or paralysis of STOMACH muscles or may be associated with other systemic diseases such as DIABETES MELLITUS.
Identifiers
References & data sources
- Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
- Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
- Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
- Related entities are derived from literature co-mention (studied together) — associative, not causal.