MFGE8

Gene

milk fat globule EGF and factor V/VIII domain containing

HGNCHGNC:7036 EnsemblENSG00000140545 NCBI Gene4240

Locus: gene with protein productLocation: 15q26.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asSPAG10 · OAcGD3S · SED1 · EDIL1 · BA46 · HsT19888 · MFG-E8 · hP47

View full nomenclature history (12)

Previous symbolsSPAG10

Alias symbolsOAcGD3S, SED1, EDIL1, BA46, HsT19888, MFG-E8, hP47

Previous namessperm associated antigen 10, milk fat globule-EGF factor 8 protein

Alias namessperm surface protein hP47, lactadherin

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Immunoglobulin Light-chain Amyloidosis

Angina Pectoris

Myocardial Ischemia

Angina, Unstable

Diabetic Ketoacidosis

Gastroparesis

Schizophrenia

Neoplasms

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.