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Disease

Hemorrhagic Fever, Ebola

Late-stage therapeutic developmentEmerging researchSteady momentum
10
Publications
7
Clinical trials
2
Related conditions
2025
Latest publication
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this disease.

Reflections on 40 Years of AIDS.

Research2021-06-01Emerging infectious diseases

Persistence of Ebola Virus in Ocular Fluid during Convalescence.

Research2015-05-07The New England journal of medicine

Understanding the dynamics of Ebola epidemics.

Research2006-09-26Epidemiology and infection

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

No activity recorded in this window. Try a wider timeframe.

Clinical trials

5 sponsors · 0 new · 0 completed in the last 12 months (net +0)

The current development programme across all trial phases.

Clinical programme
7
All trials
0
Active
2
Late-stage
6
Completed
Late-stage studies
Recently completed

[rVSVΔG-ZEBOV] Ebola Prevention Vaccine Evaluation in Sierra Leone

Phase 2/3 · Completed · Centers for Disease Control and Prevention

Research activity

10 papers

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Publications over time
20072025
Most influential
Recent publications
Major themes8
  • Hemorrhagic Fever, Ebola3
  • COVID-192
  • Acquired Immunodeficiency Syndrome1
  • Betacoronavirus1
  • CD4-Positive T-Lymphocytes1
  • Deep Learning1
  • Disease Outbreaks1
  • Ebola Vaccines1
Leading journals6
  • Lancet (London, England)2
  • Emerging infectious diseases1
  • Epidemiology and infection1
  • Journal of medical virology1
  • Nature communications1
  • Nature reviews. Genetics1
Leading researchers8
  • Fidler DP2
  • Gostin LO2
  • Heymann DL2
  • Béavogui AH1
  • Bérerd-Camara M1
  • Blackwood B1
  • Boelle PY1
  • Carpenter D1
Affiliations (unnormalised)6
  • Indiana University Maurer School of Law2
  • London School of Hygiene & Tropical Medicine2
  • Academic Medical Center1
  • Advanced Research Institute of Multidisciplinary Science1
  • Ahmadu Bello University1
  • AIDS Healthcare Foundation1

Related conditions

2 matches

Diseases frequently studied alongside this one. Number shows shared papers.

Disease profile

A grounded synthesis of the condition — overview, causes, mechanism, risk factors and current standard of care.

Overview

Ebola hemorrhagic fever is a highly fatal, acute hemorrhagic fever caused by ebolaviruses. The supplied grounding also frames it as a major epidemic-prone infectious disease of global health security concern.

Causes

It is caused by infection with ebolavirus. The grounding does not support more specific aetiologic detail beyond the viral cause.

Pathophysiology

The grounding supports that Ebola is a highly infectious disease associated with exposure to contaminated body fluids, particularly in healthcare settings. It also indicates an immunology focus in the literature, but does not provide specific mechanistic details of viral replication, immune evasion, or tissue injury.

Risk factors

Exposure to contaminated body fluids increases risk, especially for healthcare workers caring for infected patients. The literature also emphasizes epidemic settings and limited public health capacity as contexts in which transmission control is especially challenging.

Current standard of care

The grounding supports prevention and control measures rather than disease-specific curative therapy. These include personal protective equipment for healthcare workers and broader surveillance, rapid diagnosis, and real-time tracking to support outbreak control.

AI-generated summary grounded in MeSH and 5 peer-reviewed sources. Informational only — not medical advice. Generated 2026-07-07.

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

A highly fatal, acute hemorrhagic fever caused by EBOLAVIRUS.

References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.