Hereditary sensory and autonomic neuropathy type 7
Also known as CIP with hyperhidrosis and gastrointestinal dysfunction, HSAN VII, HSAN with hyperhidrosis and gastrointestinal dysfunction, HSAN7+9 more
CIP with hyperhidrosis and gastrointestinal dysfunction, HSAN VII, HSAN with hyperhidrosis and gastrointestinal dysfunction, HSAN7, SCN11A autosomal dominant hereditary sensory and autonomic neuropathy, autosomal dominant hereditary sensory and autonomic neuropathy caused by mutation in SCN11A, congenital insensitivity to pain with hyperhidrosis and gastrointestinal dysfunction, hereditary sensory and autonomic neuropathy type VII, hereditary sensory and autonomic neuropathy with hyperhidrosis and gastrointestinal dysfunction, HSAN 7, insensitivity to pain, congenital, with gastrointestinal dysfunction and hyperhidrosis, neuropathy, hereditary sensory and autonomic, type 7, neuropathy, hereditary sensory and autonomic, type VII.
What's happening now
An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.
- 4 clinical trials expected to report results, the earliest in Q2 2027.
- Q2 2027A Randomized Controlled Trial for Cervicothoracic Sympathetic Chain Block Against Sham Injection Evaluation for Post COVID Condition: the CeASE RCT
- Q2 2027Comparison of Suprainguinal Fascia Iliac Block With and Without Dexmedetomidine as an Adjunct to Ropivacaine for Postoperative Analgesia Following Hip Surgery: a Randomized, Double-blinded Study.
- Q4 2027A Randomized, Placebo-controlled, Double-blind Trial of Suzetrigine in Total Hip Arthroplasty
- Q1 2028A Study on the Effect of GLP-1 Receptor Agonist (GLP-1RA) Intervention on Cardiac Autonomic Neuropathy in Patients With Type 2 Diabetes Mellitus
Clinical MilestonesViewHide
- 2026-07-30A Randomized, Placebo-controlled, Double-blind Trial of Suzetrigine in Total Hip ArthroplastyResults expected Q4 2027
- 2026-06-08A Randomized Controlled Trial for Cervicothoracic Sympathetic Chain Block Against Sham Injection Evaluation for Post COVID Condition: the CeASE RCTResults expected Q2 2027
- 2026-04-30A Study on the Effect of GLP-1 Receptor Agonist (GLP-1RA) Intervention on Cardiac Autonomic Neuropathy in Patients With Type 2 Diabetes MellitusResults expected Q1 2028
- 2026-03-25Comparison of Suprainguinal Fascia Iliac Block With and Without Dexmedetomidine as an Adjunct to Ropivacaine for Postoperative Analgesia Following Hip Surgery: a Randomized, Double-blinded Study.Results expected Q2 2027
- 2026-05-12Efficacy and Safety of Topical Lidocaine 23%/Tetracaine 7% Ointment Versus Placebo for Post-Hemorrhoidectomy Pain: A Double-Blind Randomized Controlled TrialCompleted
- 2026-02-24A Multi-Center, Randomized, Double-Blind, Placebo/Active-Controlled Phase III Clinical Study to Evaluate the Efficacy and Safety of HSK21542 Injection for Postoperative Pain Treatment in Orthopedic SurgeryCompleted
- 2027-12-01Guard3: An Open-label, Parallel-arm, Randomized, Controlled, Phase 2/Phase 3 Study Evaluating the Efficacy and Safety of Autologous HSC Gene Therapy, AVR-RD-02, Compared to ERT for Gaucher Disease Type 3 in Participants Aged 2 to 25Withdrawn
- 2026-02-26Opioid-Free Pain Control Regimen Following Robotic Radical Prostatectomy: A Randomized Controlled TrialTerminated
- 2027-12-01ClinicalGuard3: An Open-label, Parallel-arm, Randomized, Controlled, Phase 2/Phase 3 Study Evaluating the Efficacy and Safety of Autologous HSC Gene Therapy, AVR-RD-02, Compared to ERT for Gaucher Disease Type 3 in Participants Aged 2 to 25Withdrawn
- 2026-07-30ClinicalA Randomized, Placebo-controlled, Double-blind Trial of Suzetrigine in Total Hip ArthroplastyResults expected Q4 2027
- 2026-06-08ClinicalA Randomized Controlled Trial for Cervicothoracic Sympathetic Chain Block Against Sham Injection Evaluation for Post COVID Condition: the CeASE RCTResults expected Q2 2027
- 2026-05-12ClinicalEfficacy and Safety of Topical Lidocaine 23%/Tetracaine 7% Ointment Versus Placebo for Post-Hemorrhoidectomy Pain: A Double-Blind Randomized Controlled TrialCompleted
- 2026-04-30ClinicalA Study on the Effect of GLP-1 Receptor Agonist (GLP-1RA) Intervention on Cardiac Autonomic Neuropathy in Patients With Type 2 Diabetes MellitusResults expected Q1 2028
- 2026-03-25ClinicalComparison of Suprainguinal Fascia Iliac Block With and Without Dexmedetomidine as an Adjunct to Ropivacaine for Postoperative Analgesia Following Hip Surgery: a Randomized, Double-blinded Study.Results expected Q2 2027
- 2026-02-26ClinicalOpioid-Free Pain Control Regimen Following Robotic Radical Prostatectomy: A Randomized Controlled TrialTerminated
- 2026-02-24ClinicalA Multi-Center, Randomized, Double-Blind, Placebo/Active-Controlled Phase III Clinical Study to Evaluate the Efficacy and Safety of HSK21542 Injection for Postoperative Pain Treatment in Orthopedic SurgeryCompleted
Clinical trials
The current development programme across all trial phases.
Associated genes
Genes associated with this disease in the canonical knowledge graph (Open Targets evidence). Number shows the association score.
Disease biology
Proteins whose encoding gene is associated with this disease, reached through the canonical gene→disease graph. Number shows the gene's association score.
Reference
Authoritative identity, definition & identifiers.
CIP with hyperhidrosis and gastrointestinal dysfunction, HSAN VII, HSAN with hyperhidrosis and gastrointestinal dysfunction, HSAN7, SCN11A autosomal dominant hereditary sensory and autonomic neuropathy, autosomal dominant hereditary sensory and autonomic neuropathy caused by mutation in SCN11A, congenital insensitivity to pain with hyperhidrosis and gastrointestinal dysfunction, hereditary sensory and autonomic neuropathy type VII, hereditary sensory and autonomic neuropathy with hyperhidrosis and gastrointestinal dysfunction, HSAN 7, insensitivity to pain, congenital, with gastrointestinal dysfunction and hyperhidrosis, neuropathy, hereditary sensory and autonomic, type 7, neuropathy, hereditary sensory and autonomic, type VII
- Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
- Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
- Related entities are derived from literature co-mention (studied together) — associative, not causal.