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Disease

Intelligence

Active therapeutic pipeline

Also known as cognitive ability, general cognitive ability, general cognitive function.

8
Clinical trials
12
Associated genes
10
Related proteins
Current focus
Estrogen-related gamma biologySynaptotagmin-1 biologyTherapeutic developmentMetabolic & lifestyle factors

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

Executive briefingUpdating summary…Momentum: Low
Key developments
  • 1 clinical trial expected to report results, the earliest in Q2 2027.
  • 10 industry developments reported.
Upcoming Milestones
Clinical Milestones5View
Results expected 1
Recently completed 4
Industry & Market10View all 10
+5 more in the activity timeline below
Activity timeline15

Clinical trials

8 sponsors · 3 new · 0 completed in the last 12 months (net +3)

The current development programme across all trial phases.

Clinical programme
8
All trials
6
Active
0
Late-stage
2
Completed
Recruiting

Feasibility of a Randomized Controlled Trial of Large Artificial Intelligence-Based Linguistic Models for Clinical Reasoning Training of Physical Therapy Students. A Randomized Controlled Trial

Phase 2 · Recruiting · Neuron, Spain

An Artificial Intelligence Based Approach for Selecting the Optimal Day for Triggering.

N/A · Recruiting · Fundacion Dexeus

Acquisition and Frequency Spectroscopic Evaluation of Broadband Clinical Ultrasound Raw Data for Liver Cirrhosis and Focal Pathologies Using Neural Networks for Tissue and Pathology Differentiation

N/A · Recruiting · Technische Universität Dresden

Extracorporeal Shockwave Versus Phonophoresis on Functional and Anatomical Changes Detected With Artificial Intelligence Technology in Knee Osteoarthritis

N/A · Recruiting · Cairo University

Does AI Make Clinicians More Appropriately Confident? A Randomized Study in Preterm Birth Prediction

N/A · Recruiting · Rigshospitalet, Denmark
Recently completed

Effect of Intranasal Neuropeptide on Emotion Perception in Trait Anxiety

N/A · Completed · Massachusetts General Hospital

Oxytocin and Social Cognition in Schizophrenia

Phase 2 · Completed · University of Maryland, Baltimore

Associated genes

12 matches

Genes associated with this disease in the canonical knowledge graph (Open Targets evidence). Number shows the association score.

SLC39A80.54NEGR10.53ANAPC40.52FOXO30.51SREK1IP10.50ELAVL20.50TANK0.50FOXO60.49BCL11A0.49PLCL20.48CADM20.48KCNJ30.47

Disease biology

10 matches

Proteins whose encoding gene is associated with this disease, reached through the canonical gene→disease graph. Number shows the gene's association score.

Forkhead box protein O3via FOXO30.51BCL11 transcription factor Avia BCL11A0.49Dipeptidyl peptidase 4via DPP40.43Serine/threonine-protein kinase D1via PRKD10.43Synaptotagmin-1via SYT10.43Estrogen-related receptor gammavia ESRRG0.39Orexin/Hypocretin receptor type 1via HCRTR10.35Pro-neuropeptide Yvia NPY0.29Insulin-like growth factor-binding protein 2via IGFBP20.29Large ribosomal subunit protein eL15via RPL150.27

Reference

Authoritative identity, definition & identifiers.

Synonyms

cognitive ability, general cognitive ability, general cognitive function

References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.