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Disease
Intelligence
Active therapeutic pipeline
Also known as cognitive ability, general cognitive ability, general cognitive function.
8
Clinical trials
12
Associated genes
10
Related proteins
Current focus
Estrogen-related gamma biologySynaptotagmin-1 biologyTherapeutic developmentMetabolic & lifestyle factors
What's happening now
An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.
Executive briefingUpdating summary…Momentum: Low
Key developments
- 1 clinical trial expected to report results, the earliest in Q2 2027.
- 12 industry developments reported.
Upcoming Milestones
Major developments
Upcoming trial readoutImportant
Results expected Q2 20272026-04-22
Major clinical milestoneImportant
Does AI Make Clinicians More Appropriately Confident? A Randomized Study in Preterm Birth Prediction
Primary completion2026-07-31
Clinical MilestonesViewHide
Results expected
- 2026-04-22An Artificial Intelligence Based Approach for Selecting the Optimal Day for Triggering.Results expected Q2 2027
Recently completed
- 2026-07-31Does AI Make Clinicians More Appropriately Confident? A Randomized Study in Preterm Birth PredictionPrimary completion
- 2026-07-30Feasibility of a Randomized Controlled Trial of Large Artificial Intelligence-Based Linguistic Models for Clinical Reasoning Training of Physical Therapy Students. A Randomized Controlled TrialCompleted
- 2026-06-30The Impact of AI-Powered Video-Based Discharge Education and Follow-up Intervention on Patient Outcomes and Home Care Management in Colorectal Surgery Patients Receiving Care in Line With the Postoperative Accelerated Recovery Protocol: A Mixed Methods StudyPrimary completion
- 2026-03-31Application and Effectiveness of a Large Language Model-Based Educational Agent in Medical Education: A Study on the Machine Learning and Data Mining CoursePrimary completion
Industry & MarketView all 12Hide
- 2026-10-27Industrial Intelligence: The next growth opportunity for manufacturingManufacturing · MIT Technology Review — Artificial Intelligence
- 2026-11-01[Articles] Assessment of comprehensiveness of national cancer control plans using a multiagent artificial intelligence model: a global analysisIndustry · The Lancet Oncology
- 2026-10-27Low Artificial Intelligence-Estimated Bone Mineral Density From Chest Radiographs Is Associated With Delayed Pain Recovery and Lower Quality of Life After Medial Unicompartmental Knee ArthroplastyIndustry · The Journal of Arthroplasty
- 2026-10-25A multi-source earth observation and artificial intelligence framework for unsupervised water-use anomaly screening in Mediterranean agricultureIndustry · Nature — Environmental Sciences
- 2026-10-22Artificial Intelligence, climate policy uncertainty, and renewable energy transition: nonlinear evidence on sustainable energy resilienceIndustry · Nature — Climate Sciences
+7 more in the activity timeline below
Activity timeline17
- 2026-11-01Industry[Articles] Assessment of comprehensiveness of national cancer control plans using a multiagent artificial intelligence model: a global analysisIndustry · The Lancet Oncology
- 2026-10-27IndustryIndustrial Intelligence: The next growth opportunity for manufacturingManufacturing · MIT Technology Review — Artificial Intelligence
- 2026-10-27IndustryLow Artificial Intelligence-Estimated Bone Mineral Density From Chest Radiographs Is Associated With Delayed Pain Recovery and Lower Quality of Life After Medial Unicompartmental Knee ArthroplastyIndustry · The Journal of Arthroplasty
- 2026-10-25IndustryA multi-source earth observation and artificial intelligence framework for unsupervised water-use anomaly screening in Mediterranean agricultureIndustry · Nature — Environmental Sciences
- 2026-10-25IndustryMulti-objective artificial pedosphere intelligence for microbial homeostasis-oriented governance of functional nanoparticle systems in complex ecosystemsIndustry · Nature — Environmental Sciences
- 2026-10-22IndustryA hybrid artificial intelligence framework for three-dimensional electromagnetic field mapping using airborne measurements in general aviationIndustry · Nature — Environmental Sciences
- 2026-10-22IndustryArtificial Intelligence, climate policy uncertainty, and renewable energy transition: nonlinear evidence on sustainable energy resilienceIndustry · Nature — Climate Sciences
- 2026-10-16IndustryExplainable artificial intelligence reveals spatially divergent effects of global change on mammalsIndustry · Nature — Climate Sciences
- 2026-10-14IndustrySTAT+: The startup chasing ‘general biological intelligence’Industry · STAT News
- 2026-10-14IndustryArtificial intelligence-enabled clinical phenotyping of human brown fatIndustry · Nature News
Clinical trials
The current development programme across all trial phases.
Clinical programme
8
5
0
3
Recruiting
Recently completed
Associated genes
Genes associated with this disease in the canonical knowledge graph (Open Targets evidence). Number shows the association score.
Disease biology
Proteins whose encoding gene is associated with this disease, reached through the canonical gene→disease graph. Number shows the gene's association score.
Forkhead box protein O3via FOXO30.51BCL11 transcription factor Avia BCL11A0.49Dipeptidyl peptidase 4via DPP40.43Serine/threonine-protein kinase D1via PRKD10.43Synaptotagmin-1via SYT10.43Estrogen-related receptor gammavia ESRRG0.39Orexin/Hypocretin receptor type 1via HCRTR10.35Pro-neuropeptide Yvia NPY0.29Insulin-like growth factor-binding protein 2via IGFBP20.29Large ribosomal subunit protein eL15via RPL150.27
Reference
Authoritative identity, definition & identifiers.
Synonyms
cognitive ability, general cognitive ability, general cognitive function
References & data sources
- Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
- Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
- Related entities are derived from literature co-mention (studied together) — associative, not causal.