CADM2

Gene

cell adhesion molecule 2

HGNCHGNC:29849 EnsemblENSG00000175161 NCBI Gene253559

Locus: gene with protein productLocation: 3p12.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asIGSF4D · NECL3 · Necl-3 · SynCAM2 · SynCAM-2

View full nomenclature history (7)

Previous symbolsIGSF4D

Alias symbolsNECL3, Necl-3, SynCAM2, SynCAM-2

Previous namesimmunoglobulin superfamily, member 4D

Alias namesnectin-like 3

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Glaucoma

Glaucoma, Open-Angle

Irritable Bowel Syndrome

Intelligence

Risk-taking behaviour

Smoking initiation

Attention Deficit Disorder with Hyperactivity

Obesity disorder

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

V-set domain containingC2-set domain containingI-set domain containingMicroRNA protein coding host genesNectins and nectin-like molecules

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-07-26.

Open TargetsGene–disease associations from the Open Targets Platform.