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Disease

Kallmann syndrome

Late-stage therapeutic development
Also known as Kallman syndrome, Kallman's syndrome, Olfacto-genital pathological sequence, congenital hypogonadotropic hypogonadism with anosmia+3 more

Kallman syndrome, Kallman's syndrome, Olfacto-genital pathological sequence, congenital hypogonadotropic hypogonadism with anosmia, familial hypogonadism with anosmia, hypogonadism with anosmia, hypogonadotropic hypogonadism with anosmia.

9
Clinical trials
12
Associated genes
4
Related proteins
Current focus
Neuromedin-k biologySemaphorin-3a biologyTherapeutic development

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

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Clinical trials

3 sponsors · 0 new · 0 completed in the last 12 months (net +0)

The current development programme across all trial phases.

Clinical programme
9
All trials
0
Active
1
Late-stage
5
Completed
Recently completed
Phase 1 · Completed · Massachusetts General Hospital
Phase 1 · Completed · Massachusetts General Hospital
Phase 1 · Completed · Massachusetts General Hospital
N/A · Completed · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Associated genes

12 matches

Genes associated with this disease in the canonical knowledge graph (Open Targets evidence). Number shows the association score.

Disease biology

4 matches

Proteins whose encoding gene is associated with this disease, reached through the canonical gene→disease graph. Number shows the gene's association score.

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

A genetically heterogeneous disorder caused by hypothalamic GNRH deficiency and OLFACTORY NERVE defects. It is characterized by congenital HYPOGONADOTROPIC HYPOGONADISM and ANOSMIA, possibly with additional midline defects. It can be transmitted as an X-linked (GENETIC DISEASES, X-LINKED), an autosomal dominant, or an autosomal recessive trait.

Synonyms

Kallman syndrome, Kallman's syndrome, Olfacto-genital pathological sequence, congenital hypogonadotropic hypogonadism with anosmia, familial hypogonadism with anosmia, hypogonadism with anosmia, hypogonadotropic hypogonadism with anosmia

References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.