Meniere's Disease
Recent clinical, regulatory, research and industry developments relating to this disease.
Open-Label Study of SPI-1005 for the Treatment of Meniere's Disease
What's happening now
An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.
- 1 clinical trial expected to report results, the earliest in Q1 2027.
Clinical MilestonesViewHide
- 2026-05-13Cochlear Implantation During Vestibular Schwannoma Removal or During Labyrinthectomy Surgery for Treatment of Meniere's DiseaseResults expected Q1 2027
- 2026-06-26ClinicalA Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multi-Center Study to Evaluate the Safety and Efficacy of SPI-1005 in Meniere's Disease and Open Label Extension Study to Evaluate the Chronic Safety of SPI-1005Results posted
- 2026-05-13ClinicalCochlear Implantation During Vestibular Schwannoma Removal or During Labyrinthectomy Surgery for Treatment of Meniere's DiseaseResults expected Q1 2027
- 2026-05-01ClinicalA Multicenter, Double-blinded, Randomized, Placebo-controlled Trial to Compare the Effectiveness of Intratympanic Injections methylPREDnisolon Versus Placebo in the Treatment of Vertigo Attacks in MENière's Disease (PREDMEN Trial).Primary completion
Clinical trials
The current development programme across all trial phases.
Research activity
Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.
Major themes1
- Meniere Disease1
Leading journals1
- Genes and immunity1
Leading researchers8
- Domínguez-Durán E1
- Escalera-Balsera A1
- Flook M1
- Frejo L1
- G Ranea JA1
- Gallego-Martinez A1
- Gonzalez-Aguado R1
- Lopez-Escamez JA1
Affiliations (unnormalised)6
- Hospital Clínic1
- Hospital Universitario Marques de Valdecilla1
- Hospital Universitario San Cecilio1
- Hospital Universitario Virgen Macarena1
- Institute of Biomedical Research in Malaga (IBIMA-Plataforma BIONAND)1
- Instituto de Investigación Biosanitaria1
Associated genes
Genes associated with this disease in the canonical knowledge graph (Open Targets evidence). Number shows the association score.
Reference
Authoritative identity, definition & identifiers.
A disease of the inner ear (LABYRINTH) that is characterized by fluctuating SENSORINEURAL HEARING LOSS; TINNITUS; episodic VERTIGO; and aural fullness. It is the most common form of endolymphatic hydrops.
- Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
- Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
- Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
- Related entities are derived from literature co-mention (studied together) — associative, not causal.