ST8SIA1

Gene

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1

HGNCHGNC:10869 EnsemblENSG00000111728 NCBI Gene6489

Locus: gene with protein productLocation: 12p12.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asSIAT8 · SIAT8A

View full nomenclature history (5)

Previous symbolsSIAT8, SIAT8A

Previous namessialyltransferase 8 (alpha-N-acetylneuraminate: alpha-2,8-sialytransferase, GD3 synthase) A, ST8 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase 1

Alias namesST8Sia I

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Meniere's Disease

Refractive Errors

Actinic keratosis

Central Nervous System Neoplasms

Glioma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Sialyltransferases

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.