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Disease
Pancreatitis, Chronic
Late-stage therapeutic developmentEmerging research
1
Publications
9
Clinical trials
12
Associated genes
2023
Latest publication
Latest activity
betaRecent clinical, regulatory, research and industry developments relating to this disease.
Research2023-10-10Frontiers in immunology
What's happening now
An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.
Executive briefingUpdating summary…Momentum: Low
Key developments
- 2 clinical trials expected to report results, the earliest in Q2 2027.
Upcoming Milestones
- Q2 2027Randomized, Parallel Group, Dose Escalation Trial of Pioglitazone Versus Empagliflozin for Chronic Pancreatitis/Recurrent Acute Pancreatitis Associated Diabetes Mellitus: The PEP-DM Trial
- Q4 2027Aggressive Intravenous Hydration With Lactated Ringer's Solution Plus Rectal Indometacin Versus Rectal Indometacin Alone to Prevent Pancreatitis After Pancreatic Extracorporeal Shock Wave Lithotripsy: A Multicentre, Superiority, Randomised, Controlled Trial
Major developments
Major trial resultsHigh impact
Results posted2026-06-09
Upcoming trial readoutImportant
Results expected Q2 20272026-04-03
Clinical MilestonesViewHide
Results posted
Results expected
- 2026-04-13Aggressive Intravenous Hydration With Lactated Ringer's Solution Plus Rectal Indometacin Versus Rectal Indometacin Alone to Prevent Pancreatitis After Pancreatic Extracorporeal Shock Wave Lithotripsy: A Multicentre, Superiority, Randomised, Controlled TrialResults expected Q4 2027
- 2026-04-03Randomized, Parallel Group, Dose Escalation Trial of Pioglitazone Versus Empagliflozin for Chronic Pancreatitis/Recurrent Acute Pancreatitis Associated Diabetes Mellitus: The PEP-DM TrialResults expected Q2 2027
Recently completed
Other updates
Activity timeline5
- 2026-07-02ClinicalSmoking Cessation Treatment Escalation Among Patients With Recurrent Acute Pancreatitis and Chronic PancreatitisWithdrawn
- 2026-06-09ClinicalAnti-inflammatory Therapy to Improve Outcomes in Patients With Chronic Pancreatitis Undergoing Total Pancreatectomy Islet AutotransplantationResults posted
- 2026-04-13ClinicalAggressive Intravenous Hydration With Lactated Ringer's Solution Plus Rectal Indometacin Versus Rectal Indometacin Alone to Prevent Pancreatitis After Pancreatic Extracorporeal Shock Wave Lithotripsy: A Multicentre, Superiority, Randomised, Controlled TrialResults expected Q4 2027
- 2026-04-03ClinicalRandomized, Parallel Group, Dose Escalation Trial of Pioglitazone Versus Empagliflozin for Chronic Pancreatitis/Recurrent Acute Pancreatitis Associated Diabetes Mellitus: The PEP-DM TrialResults expected Q2 2027
- 2025-10-20ClinicalOptimal Timing of Endoscopic Intervention After Extracorporeal Shock-Wave Lithotripsy in the Treatment of Chronic Pancreatitis With Pancreatic Stones.Completed
Clinical trials
The current development programme across all trial phases.
Clinical programme
9
2
3
4
Late-stage studies
Recruiting
Recently completed
Research activity
Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.
Most influential
Major themes1
- Pancreatitis, Chronic1
Leading journals1
- Frontiers in immunology1
Leading researchers7
- Asgarbeik S1
- Elsheikh H1
- Glaubitz J1
- Lange R1
- Mazloum H1
- Sendler M1
- Weiss FU1
Affiliations (unnormalised)1
- University Medicine1
Associated genes
Genes associated with this disease in the canonical knowledge graph (Open Targets evidence). Number shows the association score.
Reference
Authoritative identity, definition & identifiers.
Defined in MeSH
INFLAMMATION of the PANCREAS that is characterized by recurring or persistent ABDOMINAL PAIN with or without STEATORRHEA or DIABETES MELLITUS. It is characterized by the irregular destruction of the pancreatic parenchyma which may be focal, segmental, or diffuse.
Identifiers
References & data sources
- Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
- Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
- Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
- Related entities are derived from literature co-mention (studied together) — associative, not causal.