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SPINK1

Gene

serine peptidase inhibitor Kazal type 1

HGNCHGNC:11244EnsemblENSG00000164266NCBI Gene6690
Locus: gene with protein productLocation: 5q32

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asSpink3 · PCTT · PSTI · TATI
View full nomenclature history (5)
Alias symbolsSpink3, PCTT, PSTI, TATI
Previous namesserine protease inhibitor, Kazal type 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Hereditary chronic pancreatitis
Pancreatitis, Chronic
Pancreatitis
Pancreatic Diseases
Diabetes Mellitus
Carcinoma, Hepatocellular
Neoplasms

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Serine peptidase inhibitors, Kazal type

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.