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Disease

Phobia, Social

Late-stage therapeutic developmentEmerging research
MeSHPhobia, Social
1
Publications
3
Clinical trials
1
Associated genes
1
Related proteins
2024
Latest publication
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this disease.

Social anxiety disorder-associated gut microbiota increases social fear.

Research2023-12-26Proceedings of the National Academy of Sciences of the United States of America

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

Executive briefingUpdating summary…Momentum: Low
Key developments
  • 1 clinical trial expected to report results, the earliest in Q2 2027.
Upcoming Milestones
Major developments
Upcoming trial readoutHigh impact
Investigating the Effects of Cannabidiol on Social Anxiety Disorder
Results expected Q2 20272026-08-11
Clinical Milestones1View
Results expected 1
Activity timeline1

Clinical trials

3 sponsors · 0 new · 0 completed in the last 12 months (net +0)

The current development programme across all trial phases.

Clinical programme
3
All trials
1
Active
2
Late-stage
1
Completed
Late-stage studies

Investigating the Effects of Cannabidiol on Social Anxiety Disorder

Phase 4 · Recruiting · Massachusetts Institute of Technology

Sertraline in the Treatment of Generalized Social Phobia With Comorbidity

Phase 4 · Terminated · Hamilton Health Sciences Corporation
Recruiting

Investigating the Effects of Cannabidiol on Social Anxiety Disorder

Phase 4 · Recruiting · Massachusetts Institute of Technology

Research activity

1 papers

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Most influential

Social anxiety disorder-associated gut microbiota increases social fear.

Proceedings of the National Academy of Sciences of the United States of America · 2024 · 52 cites
Recent publications

Social anxiety disorder-associated gut microbiota increases social fear.

Proceedings of the National Academy of Sciences of the United States of America · 2024 · 52 cites
Major themes2
  • Gastrointestinal Microbiome1
  • Phobia, Social1
Leading journals1
  • Proceedings of the National Academy of Sciences of the United States of America1
Leading researchers8
  • Aburto MR1
  • Barrera-Bugueño C1
  • Bastiaanssen TFS1
  • Brocka M1
  • Butler MI1
  • Campos D1
  • Clarke G1
  • Cowan CSM1
Affiliations (unnormalised)4
  • Alimentary Pharmabiotic Centre Microbiome Ireland1
  • School of Microbiology1
  • University College Cork1
  • University Hospital Frankfurt1

Associated genes

1 match

Genes associated with this disease in the canonical knowledge graph (Open Targets evidence). Number shows the association score.

SLC6A40.59

Disease biology

1 match

Proteins whose encoding gene is associated with this disease, reached through the canonical gene→disease graph. Number shows the gene's association score.

Sodium-dependent serotonin transportervia SLC6A40.59

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

Anxiety disorder characterized by the persistent and irrational fear, anxiety, or avoidance of social or performance situations.

Identifiers
MeSHPhobia, Social
References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.