Back to discover
Drug

Aldosterone

In clinical development
Emerging researchLate-stage developmentRising momentum
Also known as (+)-aldosterone, Aldosterona, 11beta,21-Dihydroxy-3,20-dioxo-4-pregnen-18-al, 11beta,21-dihydroxy-3,20-dioxopregn-4-en-18-al+1 more

(+)-aldosterone, Aldosterona, 11beta,21-Dihydroxy-3,20-dioxo-4-pregnen-18-al, 11beta,21-dihydroxy-3,20-dioxopregn-4-en-18-al, Aldosteronum.

3
Research papers
1
Active clinical trials
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this drug.

Unmitigated Aldosterone Signaling During Standard Clinical MRA Dosing

Clinical trial2026-02-19Results expected Q3 2027 · ClinicalTrials.gov

The renin-angiotensin-aldosterone system and its suppression.

Research2019-02-26Journal of veterinary internal medicine

Aldosterone and Glucose Homeostasis

Clinical trial2017-04-06Results posted · ClinicalTrials.gov

Studies on Aldosterone and Vascular Function

Clinical trial2008-06-01Completed · ClinicalTrials.gov

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name
Aldosterone
Aliases & brands
(+)-aldosteroneAldosterona11beta,21-Dihydroxy-3,20-dioxo-4-pregnen-18-al11beta,21-dihydroxy-3,20-dioxopregn-4-en-18-alAldosteronum
RxNorm CUI
1312358
ChEMBL ID
CHEMBL273453
ATC codes
H02AA01
UNII
4964P6T9RB

Clinical trials

3 trials

The current development programme across all trial phases — status mix, phase distribution and the late-stage studies shaping the evidence base.

Development programme
CLINICALTRIALS.GOV · LIVE REGISTRY
3
registered trials across all phases
LATEST COMPLETION 2013
1
Active studies
1
Recruiting
2
Late-stage (III+)
2
Completed
PHASE DISTRIBUTIONn = 3
Phase 11Phase 41Phase N / A1

Late-stage studies

Phase III+ trials still open or recently active — where late-stage evidence is being generated.

Recent completions

Trials that read out recently, adding to the completed evidence base.

Aldosterone and Glucose Homeostasis

CompletedN/AVanderbilt Universityn=342013

Studies on Aldosterone and Vascular Function

CompletedPH IYale Universityn=202008

Research activity

3 papers

Key research shaping understanding of this drug, combining the latest publications with the most influential evidence.

Publications over time
20192024
Most influential
Recent papers
Major research themes4
Anorexia Nervosa1Cardiovascular Diseases1Hyperaldosteronism1Hypertension1
Journals, researchers & institutions
Top journals
  • Circulation1
  • European journal of endocrinology1
  • Journal of veterinary internal medicine1
Leading researchers
  • Agharazii M1
  • Ames MK1
  • Atkins CE1
  • Brown JM1
  • Crean AM1
  • Fazeli PK1
  • Goupil R1
  • Hametner B1
Leading institutions
free-text, unnormalised
  • Brigham and Women's Hospital1
  • Center for Adrenal Disorders1
  • Center for Health & Bioresources1
  • CHU de Québec-Université Laval1
  • Chulalongkorn University and Excellence Center in Diabetes1
  • Cleveland Clinic1

Related diseases

1 conditions

Regulator-approved indications and conditions co-mentioned with this drug across the research literature. Number shows shared papers.

Active research areas

Related drugs

3 matches

Drugs sharing diseases, protein targets and literature with this one. Ranked by graph evidence (shared targets + diseases weighted above co-mentions).

Studied across 2 of the same disease areas as Aldosterone in the shared literature.

2 shared diseases1 shared paper

Studied across the same disease area as Aldosterone in the shared literature.

1 shared disease1 shared paper

Studied across the same disease area as Aldosterone in the shared literature.

1 shared disease1 shared paper
References & data sources
  • RxNorm (U.S. National Library of Medicine) — drug identity
  • ChEMBL (EMBL-EBI) & UniProt — pharmacology and targets
  • Europe PMC — research literature
  • ClinicalTrials.gov — clinical trials