Hydrocortisone
Approved · FDA / EMAAlso known as 1 Plus 1 F, 11beta-hydrocortisone, 17-Hydroxycorticosterone, A-Hydrocort+205 more
1 Plus 1 F, 11beta-hydrocortisone, 17-Hydroxycorticosterone, A-Hydrocort, AK-Spore HC, Acetasol HC, Acetic Acid-Hydrocortisone, Acticort 100, Aeroseb-HC, Ala-Cort, Ala-Quin, Ala-Scalp, Alcortin, Alcortin A, Alkindi, Alocane Anti-Itch, Aloe Cort, Ana-Lex, AnaMantle HC, Analpram HC, Analpram-HC, Antibiotic Ear, Antibiotic-Cort Ear, Anucort-HC, Anusert HC-1, Anusol HC, Anusol HC-1, Anusol-HC, Aquanil HC, Aquaphor Itch Relief, Balneol, Beta HC, Beta-HC, Caldecort, Carmol HC, Cetacort, Cipro HC, Clioquinol-Hydrocortisone, Colocort, Coly Mycin S, Coly-Mycin S, Coraz, Cort-Biotic, Cort-Dome, Cortaid, Cortane, Cortane-B, Cortatrigen, Cortatrigen Modified, Cortef, Cortenema, Cortic, Corticaine, Corticool, Cortifoam, Cortisol, Cortisporin, Cortisporin-TC, Cortizone, Cotacort, Dermacort, Dermasorb AF, Dermasorb HC, Dermazene, Dermol HC, Dermolate, Dermtex HC, Drotic, Ear-Eze, Earsol-HC, Encort, Enzone, Epifoam, Evesse, Exotic-HC, Gly-Cort, Gynecort, HC-Derma-Pax, Hemmorex, Hemorrodil Plus, Hemril, Hidrocortisona, Hycort, Hydro Skin, Hydrocortisone Butyrate, Hydrocortisone Butyrate (Eqv-Locoid Lipocream), Hydrocortisone Butyrate (Eqv-Locoid), Hydrocortisone Valerate, Hydrocortisone with Aloe, Hydrocortisone, Rectal, Hydrocortisone, Topical, Hydrocortisone-Aloe, Hydrocortisone-Iodoquinol, Hydrocortisone-Lidocaine, Hydroskin, Hysone, Hytone, Instacort, Instacort 10, Ivocort, Kera-HC, Keratol HC, Khindivi, Lacticare-HC, Lazersporin-C, LidaMantle HC, Lidocort, Locoid, Malacetic, Mantadil, Masporin Otic, MiCort-HC, Micort HC, Monistat Itch Relief, MyOxin, Neo-Cortef, Neo-Polycin HC, Neotricin HC, Nogenic HC, Novacort, NuZon, Nucort, Nupercainal HC 1%, Nutracort, Ocu-Cort, Ocutricin HC, Ophthocort, Orabase HCA, Oti-Sone, Otic Care Ear, Otic Ear Care, Otic care, Oticin HC, Oticot HC, Otimar, Otirx, Otobiotic, Otocort Sterile Suspension, Pandel, Pedi-Cort V, Pediaderm HC, Pediotic, Penecort, Pramcort, Pramosone, ProCort, Procto-Kit, Procto-Med, Procto-Med HC, Procto-Pak, Proctocare-HC, Proctocort, Proctocream, Proctocream HC, Proctocream-HC, Proctofoam HC, Proctofoam-HC, Proctosert HC, Proctosol, Proctozone HC, Proctozone-H, Proctozone-HC, Recort Plus, Rectacort-HC, Rederm, Sarnol-HC, Scalacort, Scalp-Aid, Scalp-Cort, Scalpicin Itch Relief, Senatec HC, Solu-CORTEF, Steroform, Terra-Cortril, Texacort, Theracort Anti-Itch, Tri-Otic, TriOxin, Tucks HC, U-Cort, Vagisil Satin, Vanoxide-HC, Vasotate HC, Vio-Tex-HC, Vosol HC, Vytone, Westcort, Xerese, Yeast-X External, Z-Pram, ZyPram, Cortomycin, Hydrocortone, 11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione, Aloe Polysaccharides/Hydrocortisone/Iodoquinol, Genasone/Aloe, HC AC/Aloe, Hydrocortisone Acetate, Hydrocortisone Acetate-Pramoxine HCl, Hydrocortisone Hemisuccinate, Hydrocortisone Sodium Phosphate, Hydrocortisone Sodium Succinate, Hydrocortisone/Neomycin/Polymyxin B, Hydrocortisone/Neomycin/Polymyxin B, Otic, Hydrocortisonum, Hydrocortone Acetate, Hydrocortone Phosphate, Procort 1.85/1.15, Synthetic cortisol.
Recent clinical, regulatory, research and industry developments relating to this drug.
Approval: HYDROCORTISONE (ANDA218298)
Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Children and Adolescents
The cortisol axis and psychiatric disorders: an updated review.
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Profile
Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.
Pharmacology & targets
Known molecular targets and mechanisms supported by curated pharmacology databases.
Regulatory timeline
The complete regulatory record, grouped by authority — approvals, safety advisories and label changes. Each authority shows its most recent events; expand one to read its full history.
Indication: Treatment of congenital adrenal hyperplasia (CAH) in adolescents aged 12 years and over and adults.
Evidence ↗Indication: Replacement therapy of adrenal insufficiency in infants, children and adolescents (from birth to < 18 years old).
Evidence ↗Indication: Treatment of adrenal insufficiency in adults.
Evidence ↗Data from the U.S. Food and Drug Administration (U.S. Food and Drug Administration), public domain (CC0).
Contains information from the European Medicines Agency (European Medicines Agency), © EMA, reused under CC BY 4.0.
Clinical trials
The current development programme across all trial phases — status mix, phase distribution and the late-stage studies shaping the evidence base.
Late-stage studies
Phase III+ trials still open or recently active — where late-stage evidence is being generated.
Comparing Hydrocortisone and Prednisolone for Community Acquired Pneumonia (CAP)
Recent completions
Trials that read out recently, adding to the completed evidence base.
Research activity
Key research shaping understanding of this drug, combining the latest publications with the most influential evidence.
Major research themes8
Journals, researchers & institutions
- European journal of endocrinology4
- Frontiers in endocrinology3
- Biological psychiatry2
- Endocrine reviews2
- ACS sensors1
- Biomolecules1
- Arlt W3
- Bancos I3
- Newell-Price J3
- Dekkers OM2
- Fassnacht M2
- Sahdev A2
- Tabarin A2
- Terzolo M2
- Evangelismos Hospital3
- Bristol Medical School2
- Centre for Endocrinology2
- Martin-Luther-University Halle-Wittenberg2
- Mayo Clinic2
- Medical School2
Related diseases
Regulator-approved indications and conditions co-mentioned with this drug across the research literature. Number shows shared papers.
Related drugs
Drugs sharing diseases, protein targets and literature with this one. Ranked by graph evidence (shared targets + diseases weighted above co-mentions).
Acts on the same molecular target as Hydrocortisone, with 8 overlapping disease areas.
Acts on the same molecular target as Hydrocortisone, with an overlapping disease area.
Acts on the same molecular target as Hydrocortisone, with an overlapping disease area.
Studied across 6 of the same disease areas as Hydrocortisone in the shared literature.
Studied across 7 of the same disease areas as Hydrocortisone in the shared literature.
Studied across 7 of the same disease areas as Hydrocortisone in the shared literature.
Studied across 5 of the same disease areas as Hydrocortisone in the shared literature.
Studied across 6 of the same disease areas as Hydrocortisone in the shared literature.
- RxNorm (U.S. National Library of Medicine) — drug identity
- ChEMBL (EMBL-EBI) & UniProt — pharmacology and targets
- Europe PMC — research literature
- ClinicalTrials.gov — clinical trials
- Regulatory event sources are credited in the Regulatory Timeline above.