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Drug

Belnacasan

In clinical development
ClassCaspase-1 inhibitorEmerging researchEarly-to-mid development
1
Research papers
Caspase-1
Primary target
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this drug.

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name
Belnacasan
RxNorm CUI
2728046
ChEMBL ID
CHEMBL2107819
UNII
00OLE78529
Primary mechanism
Caspase-1 inhibitor

Pharmacology & targets

1 target

Known molecular targets and mechanisms supported by curated pharmacology databases.

Caspase-1
CASP1 · P29466
INHIBITORCaspase-1 inhibitor

Clinical trials

1 trials

The current development programme across all trial phases — status mix, phase distribution and the late-stage studies shaping the evidence base.

Development programme
CLINICALTRIALS.GOV · LIVE REGISTRY
1
registered trials across all phases
LATEST COMPLETION 2022
1
Completed
PHASE DISTRIBUTIONn = 1
Phase 21

Recent completions

Trials that read out recently, adding to the completed evidence base.

Research activity

1 papers

Key research shaping understanding of this drug, combining the latest publications with the most influential evidence.

Most influential

Pharmacological Inhibitors of the NLRP3 Inflammasome.

Frontiers in immunology · 2019 · 518 cites
Recent papers

Pharmacological Inhibitors of the NLRP3 Inflammasome.

Frontiers in immunology · 2019 · 518 cites
Journals, researchers & institutions
Top journals
  • Frontiers in immunology1
Leading researchers
  • Jin T1
  • Kombe AJK1
  • Li B1
  • Tao J1
  • Zahid A1
Leading institutions
free-text, unnormalised
  • CAS Center for Excellence in Molecular Cell Science1
  • Hefei National Laboratory for Physical Sciences at Microscale1
  • The First Affiliated Hospital of USTC1

Related drugs

2 matches

Drugs sharing diseases, protein targets and literature with this one. Ranked by graph evidence (shared targets + diseases weighted above co-mentions).

Frequently co-studied with Belnacasan in the research literature.

1 shared paper

Frequently co-studied with Belnacasan in the research literature.

1 shared paper
References & data sources
  • RxNorm (U.S. National Library of Medicine) — drug identity
  • ChEMBL (EMBL-EBI) & UniProt — pharmacology and targets
  • Europe PMC — research literature
  • ClinicalTrials.gov — clinical trials