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Drug

Coenzyme A

In clinical development
Emerging researchLate-stage development

Also known as 3'-phosphoadenosine-(5')diphospho(4')pantatheine, CoA.

RxNorm1314344ChEMBLCHEMBL1213327UNIISAA04E81UX
2
Research papers
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this drug.

Influenza infection elicits an expansion of gut population of endogenous Bifidobacterium animalis which protects mice against infection.

Research2020-04-28Genome biology

The Effects of Coenzyme A Combined With Statin on Serum Lipids in Patients With Hyperlipidemia: a Randomized, Double-blinded, Placebo-controlled, Multi-center Clinical Trial

Clinical trial2013-09-01Primary completion · ClinicalTrials.gov

Randomized Head-to-Head Comparison of Coenzyme A Capsule and Fenofibrate for Safety and Efficacy On Patients With Hyperlipidemia: A Phase III, Multicenter, Double-blinded, Double Dummy Clinical Trial.

Clinical trial2011-06-01Completed · ClinicalTrials.gov

Randomized Head-to-Head Comparison of Coenzyme A Capsule and Pantethine Capsule for Safety and Efficacy On Patients With Hyperlipidemia: A Phase III, Multicenter, Double-blinded, Double Dummy Clinical Trial.

Clinical trial2011-06-01Completed · ClinicalTrials.gov

The Effects of Coenzyme A on Serum Lipids in Patients With Hyperlipidemia: a Randomized, Double-blinded, Placebo-controlled, Multi-center Clinical Trial

Clinical trial2009-08-01Completed · ClinicalTrials.gov

The subsystems approach to genome annotation and its use in the project to annotate 1000 genomes.

Research2005-10-07Nucleic acids research

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name
Coenzyme A
Aliases & brands
3'-phosphoadenosine-(5')diphospho(4')pantatheineCoA
RxNorm CUI
1314344
ChEMBL ID
CHEMBL1213327
UNII
SAA04E81UX

Clinical trials

4 trials

The current development programme across all trial phases — status mix, phase distribution and the late-stage studies shaping the evidence base.

Development programme
CLINICALTRIALS.GOV · LIVE REGISTRY
4
registered trials across all phases
LATEST COMPLETION 2011
3
Late-stage (III+)
3
Completed
1
Discontinued
PHASE DISTRIBUTIONn = 4
Phase 21Phase 2 / 31Phase 32

Late-stage studies

Phase III+ trials still open or recently active — where late-stage evidence is being generated.

The Effects of Coenzyme A Combined With Statin on Serum Lipids in Patients With Hyperlipidemia: a Randomized, Double-blinded, Placebo-controlled, Multi-center Clinical Trial

Unknown statusPH II/IIIZhejiang Universityn=3202013

Randomized Head-to-Head Comparison of Coenzyme A Capsule and Fenofibrate for Safety and Efficacy On Patients With Hyperlipidemia: A Phase III, Multicenter, Double-blinded, Double Dummy Clinical Trial.

CompletedPH IIIZhejiang Universityn=4202011

Randomized Head-to-Head Comparison of Coenzyme A Capsule and Pantethine Capsule for Safety and Efficacy On Patients With Hyperlipidemia: A Phase III, Multicenter, Double-blinded, Double Dummy Clinical Trial.

CompletedPH IIIZhejiang Universityn=2402011

Research activity

2 papers

Key research shaping understanding of this drug, combining the latest publications with the most influential evidence.

Publications over time
20052020
Major research themes5
Bifidobacterium animalis1Gastrointestinal Microbiome1Genome, Archaeal1Genome, Bacterial1Software1
Journals, researchers & institutions
Top journals
  • Genome biology1
  • Nucleic acids research1
Leading researchers
  • Begley T1
  • Butler RM1
  • Cao G1
  • Chen LL1
  • Choudhuri JV1
  • Chuang HY1
  • Cohoon M1
  • de Crécy-Lagard V1
Leading institutions
free-text, unnormalised
  • College of Veterinary Medicine1
  • Hubei Key Laboratory of Agricultural Bioinformatics1
  • Key Laboratory of Development of Veterinary Diagnostic Products1
  • National Key Laboratory of Agricultural Microbiology1
  • Novogene Bioinformatics Institute1

Related drugs

2 matches

Drugs sharing diseases, protein targets and literature with this one. Ranked by graph evidence (shared targets + diseases weighted above co-mentions).

Valine

Studied across the same disease area as Coenzyme A in the shared literature.

1 shared disease1 shared paper
Leucine

Frequently co-studied with Coenzyme A in the research literature.

1 shared paper
References & data sources
  • RxNorm (U.S. National Library of Medicine) — drug identity
  • ChEMBL (EMBL-EBI) & UniProt — pharmacology and targets
  • Europe PMC — research literature
  • ClinicalTrials.gov — clinical trials