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Drug

Delandistrogene moxeparvovec

In clinical development
ClassDystrophin exogenous geneEmerging researchEarly-to-mid development

Also known as Elevidys, rAAVrh74.MHCK7.micro-dystrophin.

RxNorm2641675ChEMBLCHEMBL4650241ATCM09AX15UNII2P6QV2ZE52
1
Research papers
1
Active clinical trials
Dystrophin
Primary target
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this drug.

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name
Delandistrogene moxeparvovec
Aliases & brands
ElevidysrAAVrh74.MHCK7.micro-dystrophin
RxNorm CUI
2641675
ChEMBL ID
CHEMBL4650241
ATC codes
M09AX15
UNII
2P6QV2ZE52
Primary mechanism
Dystrophin exogenous gene

Pharmacology & targets

1 target

Known molecular targets and mechanisms supported by curated pharmacology databases.

Dystrophin
DMD · P11532
EXOGENOUS GENEDystrophin exogenous gene

Clinical trials

2 trials

The current development programme across all trial phases — status mix, phase distribution and the late-stage studies shaping the evidence base.

Development programme
CLINICALTRIALS.GOV · LIVE REGISTRY
2
registered trials across all phases
1
Active studies
1
Recruiting
1
Discontinued
PHASE DISTRIBUTIONn = 2
Phase 12

Research activity

1 papers

Key research shaping understanding of this drug, combining the latest publications with the most influential evidence.

Major research themes4
Dependovirus1Gene Therapy Agents1Genetic Therapy1Muscular Dystrophy, Duchenne1
Journals, researchers & institutions
Top journals
  • Nature medicine1
Leading researchers
  • Asher DR1
  • Ciafaloni E1
  • Darton E1
  • Elkins JS1
  • Fontoura P1
  • Guridi M1
  • Komaki H1
  • Leon-Astudillo C1
Leading institutions
free-text, unnormalised
  • Center for Gene Therapy1
  • Center for Neuromuscular Disorders in Children and Adolescents1
  • Children's Hospital of the King's Daughters1
  • Dubowitz Neuromuscular Centre1
  • Hospital Sant Joan de Déu1
  • Pediatric Neurology Institute1
References & data sources
  • RxNorm (U.S. National Library of Medicine) — drug identity
  • ChEMBL (EMBL-EBI) & UniProt — pharmacology and targets
  • Europe PMC — research literature
  • ClinicalTrials.gov — clinical trials