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Drug

Folic Acid

In clinical development
Emerging researchLate-stage developmentRising momentum
Also known as Acide folique, Acidum folicum, Anemagen, Animi-3+104 more

Acide folique, Acidum folicum, Anemagen, Animi-3, Animi-3 with Vitamin D, BiferaRx, Calafol Rx, Concept OB, Dialyvite 800, Dialyvite 800 + Iron, Dialyvite 800 with Iron, Dialyvite 800 with Zinc, Duleek-DP, Ed Cyte F, Encora AM Tablet, Encora PM Tablet, Equi-Cyte F, FA - Folic acid, FA-8, Feogen, Ferocon, Ferotrin, Ferotrinsic, Ferralet 90, Ferraplus, Ferrex 150 Forte, Ferrex 150 Forte Plus, Ferrocite F, Ferrocite Plus, Ferrogels Forte, Folacin, Folbalin, Folbecal, Folbee, Folbic, Folcaps, Folditam, Foleve, Folgard, Folgard OS, FoliNatal Plus B, Folitab, Folivane-F, Folnate, Folpace Rx, Folplex, Folsäure, Foltabs, Foltrate, Foltx, Hematogen, Hemax, Hemocyte Plus, Hemocyte-F, Hemocyte-F Elixir, Icar-C Plus, Iferex 150 Forte, Infuvite, Infuvite Pediatric, Integra F, Ircon-FA, Irofol, Irospan Tablet, Lactobacillus casei factor, Lactocal, MTX Support, MVC-Fluoride, MagneBind 400 Rx, Mi-Omega, Multigen Plus, N-pteroyl-L-glutamic acid, Natafort, Natelle, Nephro-Fer RX, Nephrocaps, Nephrocaps QT, NicAzel, Nicomide, Niferex-150 Forte, Niva-Fol, NuFol, Poly Iron 150 Forte, PreNexa, Pregnitude, Premesis Rx, Prenatal Rx 1, PteGlu, Pteroyl-L-glutamate, Pteroyl-L-glutamic acid, Pteroyl-L-monoglutamic acid, Pteroylglutamic acid, Pteroylmonoglutamic acid, Quiofic, Rena-Vite, Slow Fe with Folic Acid, Tandem F, Tandem OB, Tandem Plus, Vita-Respa, Vitabee with C, Vitafol-One, Vitamin B-9, Vitamin B9, Vitamin B>c<, Vitamin Bc, Vitamin M, ácido fólico, Folic-acid.

5
Research papers
16
Active clinical trials
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this drug.

Neurovascular Regulation During Exercise in Humans With Chronic Kidney Disease

Clinical trial2026-05-18Results expected Q2 2027 · ClinicalTrials.gov

A Study of Serum Folate Levels in Patients With Treated With Olaparib.

Clinical trial2026-03-04Results posted · ClinicalTrials.gov

Folate Receptor Alpha-A Novel Approach to Cancer Therapy.

Research2024-01-15International journal of molecular sciences

Neural tube defects.

Research2014-01-01Annual review of neuroscience

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name
Folic Acid
Aliases & brands
Acide foliqueAcidum folicumAnemagenAnimi-3Animi-3 with Vitamin DBiferaRxCalafol RxConcept OBDialyvite 800Dialyvite 800 + IronDialyvite 800 with IronDialyvite 800 with ZincDuleek-DPEd Cyte FEncora AM TabletEncora PM TabletEqui-Cyte FFA - Folic acidFA-8FeogenFeroconFerotrinFerotrinsicFerralet 90FerraplusFerrex 150 ForteFerrex 150 Forte PlusFerrocite FFerrocite PlusFerrogels ForteFolacinFolbalinFolbecalFolbeeFolbicFolcapsFolditamFoleveFolgardFolgard OSFoliNatal Plus BFolitabFolivane-FFolnateFolpace RxFolplexFolsäureFoltabsFoltrateFoltxHematogenHemaxHemocyte PlusHemocyte-FHemocyte-F ElixirIcar-C PlusIferex 150 ForteInfuviteInfuvite PediatricIntegra FIrcon-FAIrofolIrospan TabletLactobacillus casei factorLactocalMTX SupportMVC-FluorideMagneBind 400 RxMi-OmegaMultigen PlusN-pteroyl-L-glutamic acidNatafortNatelleNephro-Fer RXNephrocapsNephrocaps QTNicAzelNicomideNiferex-150 ForteNiva-FolNuFolPoly Iron 150 FortePreNexaPregnitudePremesis RxPrenatal Rx 1PteGluPteroyl-L-glutamatePteroyl-L-glutamic acidPteroyl-L-monoglutamic acidPteroylglutamic acidPteroylmonoglutamic acidQuioficRena-ViteSlow Fe with Folic AcidTandem FTandem OBTandem PlusVita-RespaVitabee with CVitafol-OneVitamin B-9Vitamin B9Vitamin B>c<Vitamin BcVitamin Mácido fólicoFolic-acid
RxNorm CUI
4511
ChEMBL ID
CHEMBL1622
ATC codes
V04CX02B03BB01B03BB51
UNII
935E97BOY8

Clinical trials

145 trials

The current development programme across all trial phases — status mix, phase distribution and the late-stage studies shaping the evidence base.

Development programme
CLINICALTRIALS.GOV · LIVE REGISTRY
145
registered trials across all phases
LATEST COMPLETION 2025
16
Active studies
13
Recruiting
83
Late-stage (III+)
78
Completed
51
Discontinued
PHASE DISTRIBUTIONn = 145
Early Phase 14Phase 111Phase 1 / 28Phase 239Phase 2 / 39Phase 324Phase 425Phase N / A25

Late-stage studies

Phase III+ trials still open or recently active — where late-stage evidence is being generated.

Recent completions

Trials that read out recently, adding to the completed evidence base.

Research activity

5 papers

Key research shaping understanding of this drug, combining the latest publications with the most influential evidence.

Publications over time
20062024
Most influential

Homocysteine lowering with folic acid and B vitamins in vascular disease.

The New England journal of medicine · 2006 · 1,113 cites

Neural tube defects.

Annual review of neuroscience · 2014 · 441 cites

Folate Receptor Alpha-A Novel Approach to Cancer Therapy.

International journal of molecular sciences · 2024 · 52 cites
Recent papers

Folate Receptor Alpha-A Novel Approach to Cancer Therapy.

International journal of molecular sciences · 2024 · 52 cites

Neural tube defects.

Annual review of neuroscience · 2014 · 441 cites

Homocysteine lowering with folic acid and B vitamins in vascular disease.

The New England journal of medicine · 2006 · 1,113 cites
Major research themes8
Carcinoma, Non-Small-Cell Lung1Depressive Disorder1Folic Acid1Lung Neoplasms1Neoplasms1Neural Tube Defects1Neurodegenerative Diseases1Suicide1
Journals, researchers & institutions
Top journals
  • International journal of molecular sciences2
  • Annual review of neuroscience1
  • Nutrients1
  • The New England journal of medicine1
Leading researchers
  • Arnold MJ1
  • Barbosa DJ1
  • Copp AJ1
  • Cunha A1
  • Fodor G1
  • Genest J Jr1
  • Gil-Martins E1
  • Gonzalez T1
Leading institutions
free-text, unnormalised
  • Associate Laboratory i4HB-Institute for Health and Bioeconomy1
  • Clinic for Adult Psychiatry1
  • Laboratory of Toxicology1
  • Memorial Cancer Institute1
  • Newlife Birth Defects Research Center1
  • Population Health Research Institute1

Related drugs

1 matches

Drugs sharing diseases, protein targets and literature with this one. Ranked by graph evidence (shared targets + diseases weighted above co-mentions).

Studied across 6 of the same disease areas as Folic Acid in the shared literature.

6 shared diseases1 shared paper
References & data sources
  • RxNorm (U.S. National Library of Medicine) — drug identity
  • ChEMBL (EMBL-EBI) & UniProt — pharmacology and targets
  • Europe PMC — research literature
  • ClinicalTrials.gov — clinical trials