Drug

Vitamin B 6

In clinical development

Emerging researchLate-stage development

Also known as Animi-3, Animi-3 with Vitamin D, Beelith, Bonjesta+50 more

Animi-3, Animi-3 with Vitamin D, Beelith, Bonjesta, Concept OB, Dialyvite 800, Dialyvite 800 + Iron, Dialyvite 800 with Iron, Dialyvite 800 with Zinc, Diclegis, Doxylamine-Pyridoxine, Eldertonic, Ellis Tonic, Encora AM Tablet, Encora PM Tablet, Ferrocite Plus, Folbecal, Foleve, Folgard OS, FoliNatal Plus B, Folnate, Folpace Rx, Hemocyte Plus, Infuvite, Infuvite Pediatric, Irospan Tablet, Lactocal, Melatonex, Multi-Delyn, Natafort, Natelle, Nephrocaps, Nephrocaps QT, NicAzel, PYRIDOXINE, Piridoxina, PreNexa, Premesis Rx, Pyridoxinum, Pyridoxol, Rena-Vite, Tandem OB, Tandem Plus, Vita-Respa, Vitabee with C, Vitafol-One, Vitamin B6 (Pyridoxine), pyridoxine (vit B6), Vitamin B6, VitaminB6, 2-methyl-3-hydroxy-4,5-dihydroxymethylpyridine, 3-hydroxy-4,5-bis(hydroxymethyl)-2-methylpyridine, 5-hydroxy-6-methyl-3,4-pyridinedimethanol, Pyridoxine Hydrochloride.

RxNorm684879 ChEMBLCHEMBL1364 ATCA11HA02UNIIKV2JZ1BI6Z

Research papers

Active clinical trials

Latest activity

beta

Recent clinical, regulatory, research and industry developments relating to this drug.

Co-SAM: An Adaptive Multi-arm Trial to Improve Clinical Outcomes Among Children Recovering From Complicated Severe Acute Malnutrition

Clinical trial2026-03-19Results expected Q3 2026 · ClinicalTrials.gov

Protecting Households On Exposure to Newly Diagnosed Index Multidrug-Resistant Tuberculosis Patients (PHOENIx MDR-TB)

Clinical trial2025-06-15Results expected Q1 2027 · ClinicalTrials.gov

Impact of Weekly Administration of Rifapentine and Isoniazid on Steady State Pharmacokinetics of Tenofovir Alafenamide in Healthy Volunteers

Clinical trial2024-08-13Results posted · ClinicalTrials.gov

Effect of Pyridoxine as Add-on Therapy With Standard Treatment in Obsessive Compulsive Disorder Patients: A Randomized, Double-Blind, Placebo-Controlled Trial

Clinical trial2024-06-15Primary completion · ClinicalTrials.gov

Short Course Low Dose Oral Colchicine After ST Elevation Myocardial Infarction(STEMI)

Clinical trial2023-12-29Primary completion · ClinicalTrials.gov

URBAN ARCH (3/5) Uganda Cohort TB Preventive Therapy for HIV-infected Alcohol Users in Uganda: an Evaluation of Safety Tolerability and Adherence

Clinical trial2023-10-19Results posted · ClinicalTrials.gov

Lactation Inhibition, the Efficiency of Vitamin B6 Versus Cabergoline- Randomized Controlled Trial

Clinical trial2022-11-07Completed · ClinicalTrials.gov

Drug-Drug Interactions Between Rifapentine and Dolutegravir in HIV/LTBI Co-Infected Individuals

Clinical trial2021-12-27Terminated · ClinicalTrials.gov

A Phase I/II Trial of the Pharmacokinetics, Tolerability, and Safety of Once-Weekly Rifapentine and Isoniazid in HIV-1-infected and HIV-1-uninfected Pregnant and Postpartum Women With Latent Tuberculosis Infection

Clinical trial2021-11-04Results posted · ClinicalTrials.gov

Phase III Clinical Trial of Ultra-Short-Course Rifapentine/Isoniazid for the Prevention of Active Tuberculosis in HIV-Infected Individuals With Latent Tuberculosis Infection

Clinical trial2021-11-04Results posted · ClinicalTrials.gov

Investigation of Pyridoxine Effect on Behavioral Adverse Events of Levetiracetam in Adult Patients With Epilepsy

Clinical trial2021-09-01Completed · ClinicalTrials.gov

Homocysteine lowering with folic acid and B vitamins in vascular disease.

Research2006-03-12The New England journal of medicine

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name

Vitamin B 6

Aliases & brands

Animi-3Animi-3 with Vitamin DBeelithBonjestaConcept OBDialyvite 800Dialyvite 800 + IronDialyvite 800 with IronDialyvite 800 with ZincDiclegisDoxylamine-PyridoxineEldertonicEllis TonicEncora AM TabletEncora PM TabletFerrocite PlusFolbecalFoleveFolgard OSFoliNatal Plus BFolnateFolpace RxHemocyte PlusInfuviteInfuvite PediatricIrospan TabletLactocalMelatonexMulti-DelynNatafortNatelleNephrocapsNephrocaps QTNicAzelPYRIDOXINEPiridoxinaPreNexaPremesis RxPyridoxinumPyridoxolRena-ViteTandem OBTandem PlusVita-RespaVitabee with CVitafol-OneVitamin B6 (Pyridoxine)pyridoxine (vit B6)Vitamin B6VitaminB62-methyl-3-hydroxy-4,5-dihydroxymethylpyridine3-hydroxy-4,5-bis(hydroxymethyl)-2-methylpyridine5-hydroxy-6-methyl-3,4-pyridinedimethanolPyridoxine Hydrochloride

RxNorm CUI

684879

ChEMBL ID

CHEMBL1364

ATC codes

A11HA02

UNII

KV2JZ1BI6Z

Clinical trials

46 trials

The current development programme across all trial phases — status mix, phase distribution and the late-stage studies shaping the evidence base.

Development programme

CLINICALTRIALS.GOV · LIVE REGISTRY

registered trials across all phases

LATEST COMPLETION 2022

Active studies

Late-stage (III+)

Completed

Discontinued

PHASE DISTRIBUTIONn = 46

Early Phase 11Phase 13Phase 1 / 24Phase 210Phase 2 / 31Phase 312Phase 45Phase N / A10

Late-stage studies

Phase III+ trials still open or recently active — where late-stage evidence is being generated.

Short Course Low Dose Oral Colchicine After ST Elevation Myocardial Infarction(STEMI)

Unknown statusPH IVNational University of Malaysian=642024

Investigation of Pyridoxine Effect on Behavioral Adverse Events of Levetiracetam in Adult Patients With Epilepsy

CompletedPH IVNasim Tabrizin=302021

URBAN ARCH (3/5) Uganda Cohort TB Preventive Therapy for HIV-infected Alcohol Users in Uganda: an Evaluation of Safety Tolerability and Adherence

CompletedPH IVUniversity of California, San Franciscon=3022021

Neuroprotective Effect of Vitamin B12 and Vitamin B6 Against Vincristine Induced Peripheral Neuropathy: A Randomized, Double Blind, Placebo Controlled, Multi Center Trial

CompletedPH IVBangabandhu Sheikh Mujib Medical University, Dhaka, Bangladeshn=882018

The Treatment of Acute Schizophrenia With High Dose Niacinmide Plus Ascorbate Plus Pyridoxine Plus Centrum Forte vs. Centrum Forte Only as an Add-On to Risperidone and Dietary Counseling

CompletedPH IVBeersheva Mental Health Centern=552008

Recent completions

Trials that read out recently, adding to the completed evidence base.

Impact of Weekly Administration of Rifapentine and Isoniazid on Steady State Pharmacokinetics of Tenofovir Alafenamide in Healthy Volunteers

CompletedPH INational Institutes of Health Clinical Center (CC)n=512022

Lactation Inhibition, the Efficiency of Vitamin B6 Versus Cabergoline- Randomized Controlled Trial

CompletedN/AHaEmek Medical Center, Israeln=892022

Investigation of Pyridoxine Effect on Behavioral Adverse Events of Levetiracetam in Adult Patients With Epilepsy

CompletedPH IVNasim Tabrizin=302021

TBTC Study 31 PK/PD: Population Pharmacokinetic and Pharmacodynamic Study of Efficacy and Safety of High-Dose Rifapentine and Moxifloxacin for Treatment of Tuberculosis in the Study 31 Treatment Trial: Intensive PK Sampling

CompletedPH IIICenters for Disease Control and Preventionn=532021

Impact of Once-Weekly Rifapentine and Isoniazid on the Steady State Pharmacokinetics of Dolutegravir and Darunavir Boosted With Cobicistat in Healthy Volunteers

CompletedPH INational Institutes of Health Clinical Center (CC)n=372021

Pyridoxine, P2 Receptor Antagonism, and ATP-mediated Vasodilation in Young Adults

CompletedPH IColorado State Universityn=92021

Research activity

1 papers

Key research shaping understanding of this drug, combining the latest publications with the most influential evidence.

Most influential

Homocysteine lowering with folic acid and B vitamins in vascular disease.

The New England journal of medicine · 2006 · 1,113 cites

Related drugs

1 matches

Drugs sharing diseases, protein targets and literature with this one. Ranked by graph evidence (shared targets + diseases weighted above co-mentions).

Folic Acid

Studied across 6 of the same disease areas as Vitamin B 6 in the shared literature.

6 shared diseases1 shared paper

References & data sources

RxNorm (U.S. National Library of Medicine) — drug identity
ChEMBL (EMBL-EBI) & UniProt — pharmacology and targets
Europe PMC — research literature
ClinicalTrials.gov — clinical trials