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Drug

Oprozomib

Early clinical development
Class26S proteasome inhibitor
38
Protein targets
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this drug.

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name
Oprozomib
RxNorm CUI
1678943
ChEMBL ID
CHEMBL2103884
UNII
MZ37792Y8J
Primary mechanism
26S proteasome inhibitor

Pharmacology & targets

38 targets

Known molecular targets and mechanisms supported by curated pharmacology databases.

INHIBITOR26S proteasome inhibitor
INHIBITOR26S proteasome inhibitor
INHIBITOR26S proteasome inhibitor
INHIBITOR26S proteasome inhibitor
INHIBITOR26S proteasome inhibitor
INHIBITOR26S proteasome inhibitor
INHIBITOR26S proteasome inhibitor
INHIBITOR26S proteasome inhibitor
INHIBITOR26S proteasome inhibitor
INHIBITOR26S proteasome inhibitor
INHIBITOR26S proteasome inhibitor
INHIBITOR26S proteasome inhibitor
INHIBITOR26S proteasome inhibitor
INHIBITOR26S proteasome inhibitor
INHIBITOR26S proteasome inhibitor
INHIBITOR26S proteasome inhibitor
INHIBITOR26S proteasome inhibitor
INHIBITOR26S proteasome inhibitor
INHIBITOR26S proteasome inhibitor
INHIBITOR26S proteasome inhibitor
INHIBITOR26S proteasome inhibitor
INHIBITOR26S proteasome inhibitor
INHIBITOR26S proteasome inhibitor
INHIBITOR26S proteasome inhibitor
INHIBITOR26S proteasome inhibitor
INHIBITOR26S proteasome inhibitor
INHIBITOR26S proteasome inhibitor
INHIBITOR26S proteasome inhibitor
INHIBITOR26S proteasome inhibitor
INHIBITOR26S proteasome inhibitor
INHIBITOR26S proteasome inhibitor
INHIBITOR26S proteasome inhibitor
INHIBITOR26S proteasome inhibitor
INHIBITOR26S proteasome inhibitor
INHIBITOR26S proteasome inhibitor
INHIBITOR26S proteasome inhibitor
INHIBITOR26S proteasome inhibitor
INHIBITOR26S proteasome inhibitor

Clinical trials

8 trials

The current development programme across all trial phases — status mix, phase distribution and the late-stage studies shaping the evidence base.

Development programme
CLINICALTRIALS.GOV · LIVE REGISTRY
8
registered trials across all phases
LATEST COMPLETION 2015
2
Completed
6
Discontinued
PHASE DISTRIBUTIONn = 8
Phase 13Phase 1 / 25
References & data sources
  • RxNorm (U.S. National Library of Medicine) — drug identity
  • ChEMBL (EMBL-EBI) & UniProt — pharmacology and targets
  • ClinicalTrials.gov — clinical trials