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Drug

Picrotoxin

Research stage
Emerging researchRising momentum
RxNorm2539172ChEMBLCHEMBL1908342UNIIZLT174DL7U
3
Research papers
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this drug.

Super-resolution imaging reveals that AMPA receptors inside synapses are dynamically organized in nanodomains regulated by PSD95.

Research2013-08-01The Journal of neuroscience : the official journal of the Society for Neuroscience

A critical role for NMDA receptors in parvalbumin interneurons for gamma rhythm induction and behavior.

Research2011-04-05Molecular psychiatry

Differential roles of NR2A and NR2B-containing NMDA receptors in cortical long-term potentiation and long-term depression.

Research2004-09-01The Journal of neuroscience : the official journal of the Society for Neuroscience

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name
Picrotoxin
RxNorm CUI
2539172
ChEMBL ID
CHEMBL1908342
UNII
ZLT174DL7U

Research activity

3 papers

Key research shaping understanding of this drug, combining the latest publications with the most influential evidence.

Publications over time
20042013
Most influential

Differential roles of NR2A and NR2B-containing NMDA receptors in cortical long-term potentiation and long-term depression.

The Journal of neuroscience : the official journal of the Society for Neuroscience · 2004 · 539 cites

A critical role for NMDA receptors in parvalbumin interneurons for gamma rhythm induction and behavior.

Molecular psychiatry · 2012 · 537 cites

Super-resolution imaging reveals that AMPA receptors inside synapses are dynamically organized in nanodomains regulated by PSD95.

The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013 · 495 cites
Recent papers

Super-resolution imaging reveals that AMPA receptors inside synapses are dynamically organized in nanodomains regulated by PSD95.

The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013 · 495 cites

A critical role for NMDA receptors in parvalbumin interneurons for gamma rhythm induction and behavior.

Molecular psychiatry · 2012 · 537 cites

Differential roles of NR2A and NR2B-containing NMDA receptors in cortical long-term potentiation and long-term depression.

The Journal of neuroscience : the official journal of the Society for Neuroscience · 2004 · 539 cites
Major research themes1
Nanostructures1
Journals, researchers & institutions
Top journals
  • The Journal of neuroscience : the official journal of the Society for Neuroscience2
  • Molecular psychiatry1
Leading researchers
  • Auberson YP1
  • Bashir ZI1
  • Brown MW1
  • Cardin JA1
  • Carlén M1
  • Choquet D1
  • Collingridge GL1
  • Constals A1
Leading institutions
free-text, unnormalised
  • Medical Research Council Centre for Synaptic Plasticity1
  • Picower Institute for Learning and Memory1
  • University of Bordeaux1

Related drugs

2 matches

Drugs sharing diseases, protein targets and literature with this one. Ranked by graph evidence (shared targets + diseases weighted above co-mentions).

Aspartic Acid

Frequently co-studied with Picrotoxin in the research literature.

1 shared paper
Ifenprodil

Frequently co-studied with Picrotoxin in the research literature.

1 shared paper
References & data sources
  • RxNorm (U.S. National Library of Medicine) — drug identity
  • ChEMBL (EMBL-EBI) & UniProt — pharmacology and targets
  • Europe PMC — research literature