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Drug

Sarcosine

In clinical development
Emerging researchEarly-to-mid development
1
Research papers
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this drug.

N-methyl-D-aspartate (NMDA) Enhancers' Benefit to Schizophrenia Treatment

Clinical trial2013-12-01Completed · ClinicalTrials.gov

N-methylglycine (Sarcosine) for Treatment of Major Depressive Disorder

Clinical trial2011-07-01Completed · ClinicalTrials.gov

NMDA Enhancers in the Treatment of Schizophrenia

Clinical trial2005-12-01Completed · ClinicalTrials.gov

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name
Sarcosine
RxNorm CUI
1362906
ChEMBL ID
CHEMBL304383
UNII
Z711V88R5F

Clinical trials

4 trials

The current development programme across all trial phases — status mix, phase distribution and the late-stage studies shaping the evidence base.

Development programme
CLINICALTRIALS.GOV · LIVE REGISTRY
4
registered trials across all phases
LATEST COMPLETION 2013
3
Completed
1
Discontinued
PHASE DISTRIBUTIONn = 4
Phase 24

Recent completions

Trials that read out recently, adding to the completed evidence base.

N-methylglycine (Sarcosine) for Treatment of Major Depressive Disorder

CompletedPH IIChina Medical University Hospitaln=402011

NMDA Enhancers in the Treatment of Schizophrenia

CompletedPH IIChina Medical University Hospitaln=202005

Research activity

1 papers

Key research shaping understanding of this drug, combining the latest publications with the most influential evidence.

Major research themes2
COVID-191Fatigue Syndrome, Chronic1
Journals, researchers & institutions
Top journals
  • Frontiers in immunology1
Leading researchers
  • Cohen Tervaert JW1
  • Elahi S1
  • Li L1
  • Luo X1
  • Osman M1
  • Redmond D1
  • Saito S1
  • Shahbaz S1
Leading institutions
free-text, unnormalised
  • Li Ka Shing Institute of Virology1
  • School of Dentistry1
  • The Metabolomics Innovation Centre1
  • University of Alberta1

Related drugs

1 matches

Drugs sharing diseases, protein targets and literature with this one. Ranked by graph evidence (shared targets + diseases weighted above co-mentions).

Studied across 4 of the same disease areas as Sarcosine in the shared literature.

4 shared diseases1 shared paper
References & data sources
  • RxNorm (U.S. National Library of Medicine) — drug identity
  • ChEMBL (EMBL-EBI) & UniProt — pharmacology and targets
  • Europe PMC — research literature
  • ClinicalTrials.gov — clinical trials