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Drug

Serine

In clinical development
Emerging researchLate-stage development
Also known as (S)-2-Amino-3-hydroxypropanoic acid, (S)-Serine, Aminosyn 10%, Sulfite-Free, Aminosyn 3.5 % M, Sulfite Free+40 more

(S)-2-Amino-3-hydroxypropanoic acid, (S)-Serine, Aminosyn 10%, Sulfite-Free, Aminosyn 3.5 % M, Sulfite Free, Aminosyn 8.5 % with Electrolytes, Sulfite-Free, Aminosyn 8.5%, Sulfite-Free, Aminosyn II 10 %, Aminosyn II 15%, Aminosyn II 8.5 % with Electrolytes, Sulfite-Free, Aminosyn II 8.5 %, Sulfite-Free, Aminosyn-HBC 7 %, Sulfite-Free, Aminosyn-PF 10 %, Sulfite-Free, Aminosyn-PF 7%, Clinisol 15, Freamine III 10, Hepatamine 8, Hepatasol, L-Serine, Plenamine, PremaSol, ProSol, ProcalAmine 3, Ser, Travasol 10, Travasol 10%, Trophamine, Trophamine 10 %, Trophamine 6 %, alpha-Amino-beta-hydroxypropionic acid, beta-Hydroxyalanine, Serina, Clinimix 4.25/10, Clinimix 4.25/25, Clinimix 4.25/5, Clinimix 5/15, Clinimix 5/20, Clinimix 5/25, Clinimix E 2.75/5, Clinimix E 4.25/10, Clinimix E 4.25/5, Clinimix E 5/15, Clinimix E 5/20, Clinimix E 5/25, Serinum.

6
Research papers
2
Active clinical trials
Latest activity
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Recent clinical, regulatory, research and industry developments relating to this drug.

Phase 3 Study of Serine Supplementation to Protect Vision in MacTel

Clinical trial2026-01-15Results expected Q4 2029 · ClinicalTrials.gov

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name
Serine
Aliases & brands
(S)-2-Amino-3-hydroxypropanoic acid(S)-SerineAminosyn 10%, Sulfite-FreeAminosyn 3.5 % M, Sulfite FreeAminosyn 8.5 % with Electrolytes, Sulfite-FreeAminosyn 8.5%, Sulfite-FreeAminosyn II 10 %Aminosyn II 15%Aminosyn II 8.5 % with Electrolytes, Sulfite-FreeAminosyn II 8.5 %, Sulfite-FreeAminosyn-HBC 7 %, Sulfite-FreeAminosyn-PF 10 %, Sulfite-FreeAminosyn-PF 7%Clinisol 15Freamine III 10Hepatamine 8HepatasolL-SerinePlenaminePremaSolProSolProcalAmine 3SerTravasol 10Travasol 10%TrophamineTrophamine 10 %Trophamine 6 %alpha-Amino-beta-hydroxypropionic acidbeta-HydroxyalanineSerinaClinimix 4.25/10Clinimix 4.25/25Clinimix 4.25/5Clinimix 5/15Clinimix 5/20Clinimix 5/25Clinimix E 2.75/5Clinimix E 4.25/10Clinimix E 4.25/5Clinimix E 5/15Clinimix E 5/20Clinimix E 5/25Serinum
RxNorm CUI
9671
ChEMBL ID
CHEMBL11298
UNII
452VLY9402

Clinical trials

7 trials

The current development programme across all trial phases — status mix, phase distribution and the late-stage studies shaping the evidence base.

Development programme
CLINICALTRIALS.GOV · LIVE REGISTRY
7
registered trials across all phases
LATEST COMPLETION 2017
2
Active studies
1
Recruiting
1
Late-stage (III+)
1
Completed
4
Discontinued
PHASE DISTRIBUTIONn = 7
Phase 1 / 22Phase 24Phase 31

Late-stage studies

Phase III+ trials still open or recently active — where late-stage evidence is being generated.

Phase 3 Study of Serine Supplementation to Protect Vision in MacTel

Not yet recruitingPH IIIThe Lowy Medical Research Institute Limitedn=1202030

Recent completions

Trials that read out recently, adding to the completed evidence base.

Research activity

6 papers

Key research shaping understanding of this drug, combining the latest publications with the most influential evidence.

Publications over time
20242025
Most influential
Recent papers
Major research themes8
Serine3Astrocytes2Amygdala1Cognition1Colorectal Neoplasms1COVID-191DNA, Mitochondrial1Fatigue Syndrome, Chronic1
Journals, researchers & institutions
Top journals
  • Cancer research2
  • Cellular and molecular life sciences : CMLS1
  • Communications biology1
  • Frontiers in immunology1
  • Nature communications1
Leading researchers
  • Ackroyd JJ1
  • Awad D1
  • Barros LF1
  • Bellocchio L1
  • Bohmbach K1
  • Bolaños JP1
  • Bollmohr N1
  • Bonvento G1
Leading institutions
free-text, unnormalised
  • Baylor College of Medicine1
  • Caryl and Israel Englander Institute for Precision Medicine1
  • Center for Nuclear Receptors and Cell Signaling1
  • Centre de Résonance Magnétique des Systèmes Biologiques1
  • CERVO Brain Research Center and Department of Biochemistry1
  • Dan L. Duncan Cancer Center1

Related drugs

1 matches

Drugs sharing diseases, protein targets and literature with this one. Ranked by graph evidence (shared targets + diseases weighted above co-mentions).

Studied across 4 of the same disease areas as Serine in the shared literature.

4 shared diseases1 shared paper
References & data sources
  • RxNorm (U.S. National Library of Medicine) — drug identity
  • ChEMBL (EMBL-EBI) & UniProt — pharmacology and targets
  • Europe PMC — research literature
  • ClinicalTrials.gov — clinical trials