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Drug

Taurine

In clinical development
Emerging researchLate-stage developmentRising momentum
Also known as Aminoethylsulfonic acid, Aminosyn-PF 10 %, Sulfite-Free, Aminosyn-PF 7%, PremaSol+5 more

Aminoethylsulfonic acid, Aminosyn-PF 10 %, Sulfite-Free, Aminosyn-PF 7%, PremaSol, Taurine-Vitamin B6, Taurineold, Trophamine, Trophamine 10 %, Trophamine 6 %.

RxNorm10337ChEMBLCHEMBL239243UNII1EQV5MLY3D
3
Research papers
5
Active clinical trials
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this drug.

An Open-Label Study of Taurine Supplementation in Adolescents With Post-COVID Condition: Quantifying Taurine Plasma Levels and Evaluating Clinical and Biological Outcomes

Clinical trial2026-07-07Results expected Q1 2028 · ClinicalTrials.gov

A Prospective, Multicentre, Double-blind Randomized Controlled Clinical Study of the Efficacy and Safety of Taurine Combined With Serplulimab and Chemotherapy Versus Serplulimab Combined With Chemotherapy for Treatment of Locally Advanced Gastric or Gastroesophageal Junction Adenocarcinoma

Clinical trial2026-06-09Results expected Q2 2027 · ClinicalTrials.gov

Taurine Supplementation as a Novel Therapeutic Approach for Neurocognitive Symptoms in Long COVID

Clinical trial2026-05-27Results expected Q1 2028 · ClinicalTrials.gov

Taurine for the Prevention and Treatment of Radiation-induced Oral Mucositis in Patients With Nasopharyngeal Carcinoma: a Single-center, Open-label, Randomized Phase 2 Clinical Trial

Clinical trial2026-05-05Results expected Q1 2027 · ClinicalTrials.gov

A Prospective, Randomized Controlled Clinical Study of The Efficacy and Safety of Taurine Combined With Sintilimab and Chemotherapy Versus Sintilimab Combined With Chemotherapy for Treatment of Advanced Gastric Cancer

Clinical trial2025-07-31Primary completion · ClinicalTrials.gov

Taurine Affects the Progression of Senile Cataract: a Single-arm Pre-post Intervention Study

Clinical trial2024-12-20Primary completion · ClinicalTrials.gov

Mitigation of aging-related plasticity decline through taurine supplementation and environmental enrichment.

Research2024-08-22Scientific reports

Taurine deficiency as a driver of aging.

Research2023-06-09Science (New York, N.Y.)

Efficacy of Subgingivally Placed Amnion Membrane With and Without Taurine as an Adjunct to Scaling and Root Planing in the Treatment of Chronic Periodontitis

Clinical trial2021-03-13Completed · ClinicalTrials.gov

Important roles of dietary taurine, creatine, carnosine, anserine and 4-hydroxyproline in human nutrition and health.

Research2020-02-18Amino acids

Taurine for Early Left Ventricular Recovery in Peripartum Cardiomyopathy

Clinical trial2020-01-01Completed · ClinicalTrials.gov

Oxidative Stress Markers In Inherited Homocystinuria And The Impact Of Taurine

Clinical trial2018-07-09Results posted · ClinicalTrials.gov

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name
Taurine
Aliases & brands
Aminoethylsulfonic acidAminosyn-PF 10 %, Sulfite-FreeAminosyn-PF 7%PremaSolTaurine-Vitamin B6TaurineoldTrophamineTrophamine 10 %Trophamine 6 %
RxNorm CUI
10337
ChEMBL ID
CHEMBL239243
UNII
1EQV5MLY3D

Clinical trials

16 trials

The current development programme across all trial phases — status mix, phase distribution and the late-stage studies shaping the evidence base.

Development programme
CLINICALTRIALS.GOV · LIVE REGISTRY
16
registered trials across all phases
LATEST COMPLETION 2021
5
Active studies
4
Recruiting
8
Late-stage (III+)
6
Completed
5
Discontinued
PHASE DISTRIBUTIONn = 16
Phase 11Phase 1 / 24Phase 23Phase 2 / 33Phase 41Phase N / A4

Late-stage studies

Phase III+ trials still open or recently active — where late-stage evidence is being generated.

The Impact of Energy Drinks on the Manual Dexterity of Final Year Dental Students

CompletedPH IVRiyadh Colleges of Dentistry and Pharmacyn=602015

Taurine Supplementation as a Novel Therapeutic Approach for Neurocognitive Symptoms in Long COVID

RecruitingPH II/IIIUniversity of Albertan=3002028

Taurine for Early Left Ventricular Recovery in Peripartum Cardiomyopathy

CompletedPH II/IIIAin Shams Universityn=402020

A 12-week, Parallel, Double-blind, Randomised, Placebo-controlled Adjunctive Study of Taurine 4 Grams in 128 Patients With First-episode Psychosis Receiving Antipsychotic Treatment.

CompletedPH II/IIIMelbourne Healthn=1212010

Recent completions

Trials that read out recently, adding to the completed evidence base.

Efficacy of Subgingivally Placed Amnion Membrane With and Without Taurine as an Adjunct to Scaling and Root Planing in the Treatment of Chronic Periodontitis

CompletedN/AMaharishi Markendeswar University (Deemed to be University)n=452021

Taurine for Early Left Ventricular Recovery in Peripartum Cardiomyopathy

CompletedPH II/IIIAin Shams Universityn=402020

Oxidative Stress Markers In Inherited Homocystinuria And The Impact Of Taurine

CompletedPH I/IIUniversity of Colorado, Denvern=152017

The Impact of Energy Drinks on the Manual Dexterity of Final Year Dental Students

CompletedPH IVRiyadh Colleges of Dentistry and Pharmacyn=602015

Taurine as an Anti-manic Agent: a Double-blind Placebo-controlled Study.

CompletedPH IIMclean Hospitaln=602011

A 12-week, Parallel, Double-blind, Randomised, Placebo-controlled Adjunctive Study of Taurine 4 Grams in 128 Patients With First-episode Psychosis Receiving Antipsychotic Treatment.

CompletedPH II/IIIMelbourne Healthn=1212010

Research activity

3 papers

Key research shaping understanding of this drug, combining the latest publications with the most influential evidence.

Publications over time
20202024
Major research themes4
Aging2Taurine2Dietary Supplements1Neuronal Plasticity1
Journals, researchers & institutions
Top journals
  • Amino acids1
  • Science (New York, N.Y.)1
  • Scientific reports1
Leading researchers
  • Ali AM1
  • Andersen JK1
  • Baumert P1
  • Biswal BK1
  • Chamoli M1
  • Charzynska A1
  • Chattopadhyay N1
  • Chawla AS1
Leading institutions
free-text, unnormalised
  • Broad Institute of Harvard and MIT1
  • Buck Institute for Research on Aging1
  • Centre for Healthy Longevity1
  • Columbia University1
  • Columbia University Irving Medical Center1
  • CSIR-Central Drug Research Institute1

Related drugs

3 matches

Drugs sharing diseases, protein targets and literature with this one. Ranked by graph evidence (shared targets + diseases weighted above co-mentions).

gamma-Aminobutyric Acid

Studied across the same disease area as Taurine in the shared literature.

1 shared disease1 shared paper
Creatine

Frequently co-studied with Taurine in the research literature.

1 shared paper
Hydroxyproline

Frequently co-studied with Taurine in the research literature.

1 shared paper
References & data sources
  • RxNorm (U.S. National Library of Medicine) — drug identity
  • ChEMBL (EMBL-EBI) & UniProt — pharmacology and targets
  • Europe PMC — research literature
  • ClinicalTrials.gov — clinical trials