gamma-Aminobutyric Acid
In clinical developmentAlso known as 4-aminobutanoic acid, 4-aminobutyric acid, 4Abu, AMINOBUTYRIC ACID+6 more
4-aminobutanoic acid, 4-aminobutyric acid, 4Abu, AMINOBUTYRIC ACID, GABA, GABA - gamma-aminobutyric acid, piperidic acid, piperidinic acid, .GAMMA.-AMINOBUTYRIC ACID, Gamma amino butyric acid.
Recent clinical, regulatory, research and industry developments relating to this drug.
Sleep, Pain and Aging: Potential Underlying Mechanisms
From bugs to brain: unravelling the GABA signalling networks in the brain-gut-microbiome axis.
Neurotransmitter power plays: the synaptic communication nexus shaping brain cancer.
Central amygdala astrocyte plasticity underlies GABAergic dysregulation in ethanol dependence.
The Glutamate/GABA-Glutamine Cycle: Insights, Updates, and Advances.
Neuronal network controlling REM sleep.
Effect of Gamma Aminobutyric Acid on ADHD and Seizures in Children With Epilepsy.
Profile
Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.
Clinical trials
The current development programme across all trial phases — status mix, phase distribution and the late-stage studies shaping the evidence base.
Late-stage studies
Phase III+ trials still open or recently active — where late-stage evidence is being generated.
Recent completions
Trials that read out recently, adding to the completed evidence base.
Sleep, Pain and Aging: Potential Underlying Mechanisms
Research activity
Key research shaping understanding of this drug, combining the latest publications with the most influential evidence.
Major research themes8
Journals, researchers & institutions
- The Journal of neuroscience : the official journal of the Society for Neuroscience8
- Translational psychiatry2
- Acta neuropathologica communications1
- Acta pharmacologica Sinica1
- Brain : a journal of neurology1
- Brain and behavior1
- Freund TF2
- Katona I2
- Mackie K2
- Sík A2
- Acsady L1
- Acsády L1
- Akerman CJ1
- Andersen JV1
- Imperial College London2
- Institute of Experimental Medicine2
- University of California2
- Bio-Mimetic Control Research Center1
- Brain Science Institute1
- Center for Cognition and Sociality1
Related diseases
Regulator-approved indications and conditions co-mentioned with this drug across the research literature. Number shows shared papers.
Related drugs
Drugs sharing diseases, protein targets and literature with this one. Ranked by graph evidence (shared targets + diseases weighted above co-mentions).
Studied across 7 of the same disease areas as gamma-Aminobutyric Acid in the shared literature.
Studied across 3 of the same disease areas as gamma-Aminobutyric Acid in the shared literature.
Studied across 3 of the same disease areas as gamma-Aminobutyric Acid in the shared literature.
Studied across 3 of the same disease areas as gamma-Aminobutyric Acid in the shared literature.
Studied across 3 of the same disease areas as gamma-Aminobutyric Acid in the shared literature.
Studied across 3 of the same disease areas as gamma-Aminobutyric Acid in the shared literature.
Studied across 3 of the same disease areas as gamma-Aminobutyric Acid in the shared literature.
Studied across 3 of the same disease areas as gamma-Aminobutyric Acid in the shared literature.
- RxNorm (U.S. National Library of Medicine) — drug identity
- ChEMBL (EMBL-EBI) & UniProt — pharmacology and targets
- Europe PMC — research literature
- ClinicalTrials.gov — clinical trials