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Drug

Tetrodotoxin

In clinical development
Emerging researchLate-stage developmentRising momentum
3
Research papers
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this drug.

Experience and activity-dependent maturation of perisomatic GABAergic innervation in primary visual cortex during a postnatal critical period.

Research2004-10-01The Journal of neuroscience : the official journal of the Society for Neuroscience

Binocular impulse blockade prevents the formation of ocular dominance columns in cat visual cortex.

Research1986-08-01The Journal of neuroscience : the official journal of the Society for Neuroscience

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name
Tetrodotoxin
RxNorm CUI
10425
ChEMBL ID
CHEMBL507974
UNII
3KUM2721U9

Clinical trials

6 trials

The current development programme across all trial phases — status mix, phase distribution and the late-stage studies shaping the evidence base.

Development programme
CLINICALTRIALS.GOV · LIVE REGISTRY
6
registered trials across all phases
LATEST COMPLETION 2018
2
Late-stage (III+)
4
Completed
2
Discontinued
PHASE DISTRIBUTIONn = 6
Phase 12Phase 22Phase 32

Recent completions

Trials that read out recently, adding to the completed evidence base.

Research activity

3 papers

Key research shaping understanding of this drug, combining the latest publications with the most influential evidence.

Publications over time
19862023
Most influential

Experience and activity-dependent maturation of perisomatic GABAergic innervation in primary visual cortex during a postnatal critical period.

The Journal of neuroscience : the official journal of the Society for Neuroscience · 2004 · 515 cites

Binocular impulse blockade prevents the formation of ocular dominance columns in cat visual cortex.

The Journal of neuroscience : the official journal of the Society for Neuroscience · 1986 · 469 cites
Recent papers

Experience and activity-dependent maturation of perisomatic GABAergic innervation in primary visual cortex during a postnatal critical period.

The Journal of neuroscience : the official journal of the Society for Neuroscience · 2004 · 515 cites

Binocular impulse blockade prevents the formation of ocular dominance columns in cat visual cortex.

The Journal of neuroscience : the official journal of the Society for Neuroscience · 1986 · 469 cites
Major research themes4
Functional Laterality1Induced Pluripotent Stem Cells1Neuronal Plasticity1Photic Stimulation1
Journals, researchers & institutions
Top journals
  • The Journal of neuroscience : the official journal of the Society for Neuroscience2
  • Stem cell reports1
Leading researchers
  • Chattopadhyaya B1
  • Ciptasari U1
  • Di Cristo G1
  • Esteve-Codina A1
  • Franke B1
  • Frega M1
  • Harris WA1
  • Higashiyama H1
Leading institutions
free-text, unnormalised
  • Centre for Genomic Regulation1
  • Cold Spring Harbor Laboratory1
  • Department of Clinical Neurophysiology1
  • Radboud University Medical Center1

Related drugs

1 matches

Drugs sharing diseases, protein targets and literature with this one. Ranked by graph evidence (shared targets + diseases weighted above co-mentions).

Frequently co-studied with Tetrodotoxin in the research literature.

1 shared paper
References & data sources
  • RxNorm (U.S. National Library of Medicine) — drug identity
  • ChEMBL (EMBL-EBI) & UniProt — pharmacology and targets
  • Europe PMC — research literature
  • ClinicalTrials.gov — clinical trials