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Drug

Vidarabine

In clinical development
ClassHuman herpesvirus 1 DNA polymerase inhibitorEmerging researchLate-stage developmentCooling momentum
Also known as 9-beta-D-Arabinofuranosyladenine, 9-beta-D-arabinofuranosyl-9H-purin-6-amine, 9-beta-D-arabinofuranosyl-adenine, Spongoadenosine+2 more

9-beta-D-Arabinofuranosyladenine, 9-beta-D-arabinofuranosyl-9H-purin-6-amine, 9-beta-D-arabinofuranosyl-adenine, Spongoadenosine, Vira-A, Vidarabinum.

5
Research papers
DNA polymerase catalytic subunit
Primary target
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this drug.

CD19 CAR T-Cell Therapy in Autoimmune Disease - A Case Series with Follow-up.

Research2024-02-01The New England journal of medicine

KTE-X19 CAR T-Cell Therapy in Relapsed or Refractory Mantle-Cell Lymphoma.

Research2020-04-01The New England journal of medicine

Ibrutinib-Rituximab or Chemoimmunotherapy for Chronic Lymphocytic Leukemia.

Research2019-08-01The New England journal of medicine

Adoptive cell therapy for patients with metastatic melanoma: evaluation of intensive myeloablative chemoradiation preparative regimens.

Research2008-09-22Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name
Vidarabine
Aliases & brands
9-beta-D-Arabinofuranosyladenine9-beta-D-arabinofuranosyl-9H-purin-6-amine9-beta-D-arabinofuranosyl-adenineSpongoadenosineVira-AVidarabinum
RxNorm CUI
11194
ChEMBL ID
CHEMBL1090
ATC codes
S01AD06J05AB03
UNII
FA2DM6879K
Primary mechanism
Human herpesvirus 1 DNA polymerase inhibitor

Pharmacology & targets

1 target

Known molecular targets and mechanisms supported by curated pharmacology databases.

INHIBITORHuman herpesvirus 1 DNA polymerase inhibitor

Clinical trials

1 trials

The current development programme across all trial phases — status mix, phase distribution and the late-stage studies shaping the evidence base.

Development programme
CLINICALTRIALS.GOV · LIVE REGISTRY
1
registered trials across all phases
LATEST COMPLETION 1990
1
Late-stage (III+)
1
Completed
PHASE DISTRIBUTIONn = 1
Phase 31

Late-stage studies

Phase III+ trials still open or recently active — where late-stage evidence is being generated.

Recent completions

Trials that read out recently, adding to the completed evidence base.

Research activity

5 papers

Key research shaping understanding of this drug, combining the latest publications with the most influential evidence.

Publications over time
20082024
Most influential
Recent papers
Major research themes8
Immunotherapy, Adoptive2Adoptive Transfer1Antigens, CD191Immunotherapy1Lupus Erythematosus, Systemic1Lymphocyte Depletion1Myeloablative Agonists1Myositis1
Journals, researchers & institutions
Top journals
  • The New England journal of medicine3
  • Journal of clinical oncology : official journal of the American Society of Clinical Oncology1
  • The Lancet. Oncology1
Leading researchers
  • Flinn IW2
  • Goy A2
  • Hill BT2
  • Jacobson CA2
  • Locke FL2
  • McSweeney PA2
  • Miklos DB2
  • Munoz J2
Leading institutions
free-text, unnormalised
  • and the Institute of Clinical Microbiology1
  • Banner MD Anderson Cancer Center1
  • City of Hope National Medical Center1
  • Cleveland Clinic Foundation1
  • Colorado Blood Cancer Institute1
  • Dana-Farber Cancer Institute1

Related drugs

5 matches

Drugs sharing diseases, protein targets and literature with this one. Ranked by graph evidence (shared targets + diseases weighted above co-mentions).

Studied across 11 of the same disease areas as Vidarabine in the shared literature.

11 shared diseases5 shared papers

Studied across 11 of the same disease areas as Vidarabine in the shared literature.

11 shared diseases4 shared papers

Studied across 3 of the same disease areas as Vidarabine in the shared literature.

3 shared diseases1 shared paper

Studied across the same disease area as Vidarabine in the shared literature.

1 shared disease1 shared paper

Studied across the same disease area as Vidarabine in the shared literature.

1 shared disease1 shared paper
References & data sources
  • RxNorm (U.S. National Library of Medicine) — drug identity
  • ChEMBL (EMBL-EBI) & UniProt — pharmacology and targets
  • Europe PMC — research literature
  • ClinicalTrials.gov — clinical trials