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ACADM

Gene

acyl-CoA dehydrogenase medium chain

HGNCHGNC:89EnsemblENSG00000117054NCBI Gene34
Locus: gene with protein productLocation: 1p31.1

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Medium-chain specific acyl-CoA dehydrogenase, mitochondrialP11310

Protein · therapeutic target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asMCAD · MCADH · ACAD1
View full nomenclature history (5)
Alias symbolsMCAD, MCADH, ACAD1
Previous namesacyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain
Alias namesmedium-chain acyl-CoA dehydrogenase

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Genetic Diseases, Inborn
Skin Diseases
Heart Diseases

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Acyl-CoA dehydrogenase familyFlavoproteins

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-03-15.
Open TargetsGene–disease associations from the Open Targets Platform.