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ACTL6B

Gene

actin like 6B

HGNCHGNC:160EnsemblENSG00000077080NCBI Gene51412
Locus: gene with protein productLocation: 7q22.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asACTL6 · BAF53B · SMARCN2
View full nomenclature history (4)
Previous symbolsACTL6
Alias symbolsBAF53B, SMARCN2
Previous namesactin-like 6

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Genetic developmental and epileptic encephalopathy
Autism Spectrum Disorder
early-infantile DEE
Genetic Diseases, Inborn
Complex neurodevelopmental disorder
Undetermined early-onset epileptic encephalopathy
Autistic Disorder

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Actin related proteinsBAF complex subunitsPBAF complex subunitsGBAF complex subunits

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.