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Disease

Complex neurodevelopmental disorder

12
Associated genes
7
Related proteins

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An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

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Associated genes

12 matches

Genes associated with this disease in the canonical knowledge graph (Open Targets evidence). Number shows the association score.

SCN2A0.67SCN8A0.64GRIN2B0.62DYRK1A0.62SYNGAP10.62SHANK20.59CHD20.57ZNRF30.54CRNKL10.53GRIK20.51RFX30.50SCAF40.50

Disease biology

7 matches

Proteins whose encoding gene is associated with this disease, reached through the canonical gene→disease graph. Number shows the gene's association score.

Sodium channel protein type 2 subunit alphavia SCN2A0.67Sodium channel protein type 8 subunit alphavia SCN8A0.64Glutamate receptor ionotropic, NMDA 2Bvia GRIN2B0.62Glutamate receptor ionotropic, kainate 2via GRIK20.51Disks large homolog 4via DLG40.4626S proteasome non-ATPase regulatory subunit 12via PSMD120.37Histone-lysine N-methyltransferase KMT5Bvia KMT5B0.37
References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.