CRNKL1

Gene

crooked neck pre-mRNA splicing factor 1

HGNCHGNC:15762 EnsemblENSG00000101343 NCBI Gene51340

Locus: gene with protein productLocation: 20p11.23

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCRN · CLF · SYF3 · Clf1

View full nomenclature history (8)

Alias symbolsCRN, CLF, SYF3, Clf1

Previous namescrooked neck (Drosophila Crn homolog)-like 1, Crn, crooked neck-like 1 (Drosophila), crooked neck pre-mRNA splicing factor-like 1 (Drosophila)

Alias namesSYF3 pre-mRNA-splicing factor

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Complex neurodevelopmental disorder

Dengue

Diabetes Mellitus, Type 2

Leukemia, Myeloid, Acute

Urinary bladder carcinoma

Carcinoma, Hepatocellular

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Spliceosomal B complexSpliceosomal Bact complexSpliceosomal C complexSpliceosomal P complex

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.