ADAMTS2

Gene

ADAM metallopeptidase with thrombospondin type 1 motif 2

HGNCHGNC:218 EnsemblENSG00000087116 NCBI Gene9509

Locus: gene with protein productLocation: 5q35.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asADAMTS-3 · hPCPNI · PCINP · ADAM-TS2 · NPI

View full nomenclature history (8)

Alias symbolsADAMTS-3, hPCPNI, PCINP, ADAM-TS2, NPI

Previous namesa disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 2

Alias namesprocollagen I N-proteinase, procollagen N-endopeptidase

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Spondylitis, Ankylosing

Placental abruption

Neoplasms

Drug Hypersensitivity

Chondrocalcinosis

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

ADAM metallopeptidases with thrombospondin type 1 motif

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.