Disease

Placental abruption

Late-stage therapeutic development

Also known as Abruptio placentae, premature separation of placenta, abruptio placenta, abruptio placentae, placental abruption (disease)+1 more

Abruptio placentae, premature separation of placenta, abruptio placenta, abruptio placentae, placental abruption (disease), premature separation of placenta.

Clinical trials

Associated genes

Related proteins

Current focus

Netrin-1 biologySomatostatin biologyTherapeutic development

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

Executive briefingUpdating summary…Momentum: Low

Key developments

1 clinical trial expected to report results, the earliest in Q1 2029.

Upcoming Milestones

Q1 2029Chronic Hypertension and Acetyl Salicylic Acid in Pregnancy, a Multicenter Prospective Randomized Double-blind Placebo-controlled Trial.

Major developments

Upcoming trial readoutHigh impact

Chronic Hypertension and Acetyl Salicylic Acid in Pregnancy, a Multicenter Prospective Randomized Double-blind Placebo-controlled Trial.

Results expected Q1 20292026-06-12

Clinical Milestones1View

Results expected 1

2026-06-12Chronic Hypertension and Acetyl Salicylic Acid in Pregnancy, a Multicenter Prospective Randomized Double-blind Placebo-controlled Trial.Results expected Q1 2029

Activity timeline1

2026-06-12ClinicalChronic Hypertension and Acetyl Salicylic Acid in Pregnancy, a Multicenter Prospective Randomized Double-blind Placebo-controlled Trial.Results expected Q1 2029

Clinical trials

1 sponsors · 0 new · 0 completed in the last 12 months (net +0)

The current development programme across all trial phases.

Clinical programme

All trials

Active

Late-stage

Completed

Late-stage studies

Chronic Hypertension and Acetyl Salicylic Acid in Pregnancy, a Multicenter Prospective Randomized Double-blind Placebo-controlled Trial.

Phase 3 · Recruiting · Centre Hospitalier Intercommunal Creteil

Recruiting

Chronic Hypertension and Acetyl Salicylic Acid in Pregnancy, a Multicenter Prospective Randomized Double-blind Placebo-controlled Trial.

Phase 3 · Recruiting · Centre Hospitalier Intercommunal Creteil

Associated genes

12 matches

Genes associated with this disease in the canonical knowledge graph (Open Targets evidence). Number shows the association score.

SOX110.43 SLC24A20.42 CTNNA30.41 DPP100.40 FGF140.40 SIM10.39 KCNIP40.38 FOCAD0.38 PRDM20.38 ZCCHC20.37 DSCAML10.36 RBMS30.35

Disease biology

9 matches

Proteins whose encoding gene is associated with this disease, reached through the canonical gene→disease graph. Number shows the gene's association score.

Leucine-rich repeat serine/threonine-protein kinase 2via LRRK20.34 Somatostatinvia SST0.33 Tissue factorvia F30.30 Short transient receptor potential channel 6via TRPC60.29 Netrin-1via NTN10.29 Protein-glutamine gamma-glutamyltransferase 2via TGM20.29 Proto-oncogene Masvia MAS10.28 Integrin beta-1via ITGB10.28 Osteopontinvia SPP10.27

Reference

Authoritative identity, definition & identifiers.

Synonyms

Abruptio placentae, premature separation of placenta, abruptio placenta, abruptio placentae, placental abruption (disease), premature separation of placenta

References & data sources

Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
Related entities are derived from literature co-mention (studied together) — associative, not causal.