PRDM2

Gene

PR/SET domain 2

HGNCHGNC:9347 EnsemblENSG00000116731 NCBI Gene7799

Locus: gene with protein productLocation: 1p36.21

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asRIZ · RIZ1 · RIZ2 · KMT8 · MTB-ZF · HUMHOXY1 · KMT8A

View full nomenclature history (14)

Alias symbolsRIZ, RIZ1, RIZ2, KMT8, MTB-ZF, HUMHOXY1, KMT8A

Previous namesPR domain containing 2, with ZNF domain, PR domain 2

Alias namesretinoblastoma protein-binding zinc finger protein, retinoblastoma protein-interacting zinc finger protein, MTE-binding protein, zinc-finger DNA-binding protein, GATA-3 binding protein G3B

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Placental abruption

Liver Diseases

Intracranial Aneurysm

Carcinoma, Hepatocellular

Wounds and Injuries

Carcinoma, Renal Cell

Glioma

Alcohol drinking

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Zinc fingers C2H2-typePR/SET domain familyPutative lysine methyltransferases

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-03-15.

Open TargetsGene–disease associations from the Open Targets Platform.