ADGRG2

Gene

adhesion G protein-coupled receptor G2

HGNCHGNC:4516 EnsemblENSG00000173698 NCBI Gene10149

Locus: gene with protein productLocation: Xp22.13

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asGPR64 · HE6 · TM7LN2 · EDDM6

View full nomenclature history (6)

Previous symbolsGPR64

Alias symbolsHE6, TM7LN2, EDDM6

Previous namesG protein-coupled receptor 64

Alias namesepididymal protein 6

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

congenital bilateral aplasia of vas deferens from CFTR mutation

Congenital bilateral absence of vas deferens

Genetic Diseases, Inborn

Hypertension

Sarcoma, Ewing

Endometrial Neoplasms

Carcinoma, Hepatocellular

Spermatogenic failure

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Adhesion G protein-coupled receptors, subfamily G

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.