Back to discover

AGL

Gene

amylo-alpha-1,6-glucosidase and 4-alpha-glucanotransferase

HGNCHGNC:321EnsemblENSG00000162688NCBI Gene178
Locus: gene with protein productLocation: 1p21.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asGDE
View full nomenclature history (5)
Alias symbolsGDE
Previous namesamylo-1, 6-glucosidase, 4-alpha-glucanotransferase, amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
Alias namesglycogen debranching enzyme, glycogen storage disease type III

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Glycogen Storage Disease
Genetic Diseases, Inborn
Meniere's Disease

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Glycoside hydrolase family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2024-10-17.
Open TargetsGene–disease associations from the Open Targets Platform.