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AGR2

Gene

anterior gradient 2, protein disulphide isomerase family member

HGNCHGNC:328EnsemblENSG00000106541NCBI Gene10551
Locus: gene with protein productLocation: 7p21.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asXAG-2 · HAG-2 · AG2 · PDIA17
View full nomenclature history (6)
Alias symbolsXAG-2, HAG-2, AG2, PDIA17
Previous namesanterior gradient 2 homolog (Xenopus laevis)
Alias namesprotein disulfide isomerase family A, member 17

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Bronchiectasis with or without elevated sweat chloride 1
Alcohol drinking
Cutaneous melanoma
Neoplasms

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Protein disulfide isomerases

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.