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ALKBH1

Gene

alkB homolog 1, histone H2A dioxygenase

HGNCHGNC:17911EnsemblENSG00000100601NCBI Gene8846
Locus: gene with protein productLocation: 14q24.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asALKBH · hABH · alkB · ABH
View full nomenclature history (6)
Previous symbolsALKBH
Alias symbolshABH, alkB, ABH
Previous namesalkB, alkylation repair homolog 1 (E. coli), alkB, alkylation repair homolog (E. coli)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Musculoskeletal Diseases
Neurodegenerative Diseases
Gastric adenocarcinoma
Fatty Liver
Glioblastoma
Carcinoma, Hepatocellular

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Alkylation repair homologsDNA-(apurinic or apyrimidinic site) lyases

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.