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ALOXE3

Gene

arachidonate epidermal lipoxygenase 3

HGNCHGNC:13743EnsemblENSG00000179148NCBI Gene59344
Locus: gene with protein productLocation: 17p13.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known aseLOX3 · E-LOX
View full nomenclature history (7)
Alias symbolseLOX3, E-LOX
Previous namesarachidonate lipoxygenase 3
Alias namesEpidermal lipoxygenase-3, hydroperoxide isomerase, hydroperoxy icosatetraenoate isomerase, hydroperoxy icosatetraenoate dehydratase

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Scoliosis

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Arachidonate lipoxygenasesHydroperoxy icosatetraenoate dehydratases

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2024-08-08.
Open TargetsGene–disease associations from the Open Targets Platform.