Back to discover

AP4E1

Gene

adaptor related protein complex 4 subunit epsilon 1

HGNCHGNC:573EnsemblENSG00000081014NCBI Gene23431
Locus: gene with protein productLocation: 15q21.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asAP-4-EPSILON · SPG51
View full nomenclature history (3)
Alias symbolsAP-4-EPSILON, SPG51
Previous namesadaptor related protein complex 4 epsilon 1 subunit

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Osteoarthritis
Keloid

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Clathrin/coatomer adaptor, adaptin-like, N-terminal domain containingAdaptor related protein complex 4

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.