Keloid
Recent clinical, regulatory, research and industry developments relating to this disease.
The Communication from Immune Cells to the Fibroblasts in Keloids: Implications for Immunotherapy.
What's happening now
An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.
- 3 clinical trials expected to report results, the earliest in Q3 2026.
- Q3 2026A Randomized Controlled Trial Comparing The Effectiveness And Safety Of iIntralesional 5 Flourouracil Monotherapy Verses 5 Flourouracil Combined With Cryotherapy; In The Treatment Of Keloid Scars
- Q2 2027Topical Cryotherapy to Reduce Pain During Steroid Injections for Keloid and Hypertrophic Scars: A Pilot Study
- Q3 2027A Single-Center, Two-Arm, Open-Label Phase IIA Clinical Trial to Investigate Efficacy and Safety of Ritlecitinib in Patients With Keloid
Clinical MilestonesViewHide
- 2026-06-12Topical Cryotherapy to Reduce Pain During Steroid Injections for Keloid and Hypertrophic Scars: A Pilot StudyResults expected Q2 2027
- 2026-04-24A Randomized Controlled Trial Comparing The Effectiveness And Safety Of iIntralesional 5 Flourouracil Monotherapy Verses 5 Flourouracil Combined With Cryotherapy; In The Treatment Of Keloid ScarsResults expected Q3 2026
- 2025-09-30A Single-Center, Two-Arm, Open-Label Phase IIA Clinical Trial to Investigate Efficacy and Safety of Ritlecitinib in Patients With KeloidResults expected Q3 2027
- 2026-06-30ClinicalComparison of Recurrence Rate of Keloid After Excision Between Intra-operative Steroid Injection and Steroid With Platelet-rich Plasma Injection Combination TherapyPrimary completion
- 2026-06-12ClinicalTopical Cryotherapy to Reduce Pain During Steroid Injections for Keloid and Hypertrophic Scars: A Pilot StudyResults expected Q2 2027
- 2026-04-24ClinicalA Randomized Controlled Trial Comparing The Effectiveness And Safety Of iIntralesional 5 Flourouracil Monotherapy Verses 5 Flourouracil Combined With Cryotherapy; In The Treatment Of Keloid ScarsResults expected Q3 2026
- 2025-09-30ClinicalA Single-Center, Two-Arm, Open-Label Phase IIA Clinical Trial to Investigate Efficacy and Safety of Ritlecitinib in Patients With KeloidResults expected Q3 2027
Clinical trials
The current development programme across all trial phases.
Research activity
Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.
Major themes1
- Keloid1
Leading journals1
- International journal of molecular sciences1
Leading researchers3
- Li D1
- Wu X1
- Zhang X1
Affiliations (unnormalised)3
- Hospital for Skin Diseases1
- Jiangsu Key Laboratory of Molecular Biology for Skin Diseases and STIs1
- Key Laboratory of Basic and Translational Research on Immune-Mediated Skin Diseases1
Reference
Authoritative identity, definition & identifiers.
A sharply elevated, irregularly shaped, progressively enlarging scar resulting from formation of excessive amounts of collagen in the dermis during connective tissue repair. It is differentiated from a hypertrophic scar (CICATRIX, HYPERTROPHIC) in that the former does not spread to surrounding tissues.
- Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
- Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
- Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
- Related entities are derived from literature co-mention (studied together) — associative, not causal.