HEMK2

Gene

HemK methyltransferase 2, ETF1 glutamine and histone H4 lysine

HGNCHGNC:16021 EnsemblENSG00000156239 NCBI Gene29104

Locus: gene with protein productLocation: 21q21.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asN6AMT1 · C21orf127 · PRED28 · N6AMT · MTQ2 · KMT9 · PrmC

View full nomenclature history (11)

Previous symbolsN6AMT1, C21orf127

Alias symbolsPRED28, N6AMT, MTQ2, KMT9, PrmC

Previous namesN-6 adenine-specific DNA methyltransferase 1 (putative), chromosome 21 open reading frame 127, HemK methyltransferase family member 2, N-6 adenine-specific DNA methyltransferase 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Keloid

Diabetes, Gestational

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Glutamine methyltransferases7BS protein glutamine methyltransferases

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2025-09-17.

Open TargetsGene–disease associations from the Open Targets Platform.