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APCS

Gene

amyloid P component, serum

HGNCHGNC:584EnsemblENSG00000132703NCBI Gene325
Locus: gene with protein productLocation: 1q23.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asSAP · PTX2 · MGC88159
View full nomenclature history (6)
Alias symbolsSAP, PTX2, MGC88159
Alias namespentraxin-related, 9.5S alpha-1-glycoprotein, pentraxin-2

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Immunoglobulin Light-chain Amyloidosis
Splenic Diseases
Restless Legs Syndrome
Bacterial Infections
Retinal Dystrophies
Amyloidosis
Lupus Erythematosus, Systemic

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Short pentraxins

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.