Back to discover

ARHGEF26

Gene

Rho guanine nucleotide exchange factor 26

HGNCHGNC:24490EnsemblENSG00000114790NCBI Gene26084
Locus: gene with protein productLocation: 3q25.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asDKFZP434D146 · SGEF
View full nomenclature history (4)
Alias symbolsDKFZP434D146, SGEF
Previous namesRho guanine nucleotide exchange factor (GEF) 26
Alias namesSrc homology 3 domain-containing guanine nucleotide exchange factor

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases
Coronary Artery Disease
Aortic Valve Stenosis
Myocardial Ischemia
Prostate carcinoma
Heart Diseases

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Pleckstrin homology domain containingDbl family Rho GEFs

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.